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Chondrocytes derived from mesenchymal stromal cells and induced pluripotent cells of patients with familial osteochondritis dissecans exhibit an endoplasmic reticulum stress response and defective matrix assembly
(Wiley, 2016-07-07)
Familial osteochondritis dissecans (FOCD) is an inherited skeletal defect characterized by the development of large cartilage lesions in multiple joints, short stature, and early onset of severe osteoarthritis. It is ...
Integrated analyses of microbiome and longitudinal metabolome data reveal microbial-host interactions on sulfur metabolism in Parkinson's disease.
(Elsevier, 2019-11-12)
Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging roles for the gut microbiome. Here, we integrate longitudinal metabolome data from 30 drug-naive, de novo PD patients and 30 matched ...
Adjustment disorder and suicidal behaviours presenting in the general medical setting: A systematic review
(MDPI, 2019-08-18)
Background: Adjustment disorder (AD) is a condition commonly encountered by clinicians in emergency departments and liaison psychiatry settings and has been frequently reported among patients presenting with suicidal ...
Antimicrobial management and appropriateness of treatment of urinary tract infection in general practice in Ireland
(2011)
ABSTRACT: BACKGROUND: Urinary tract infections (UTIs) are the second most common bacterial infections in general practice and a frequent indication for prescription of antimicrobials. Increasing concern about the association ...
Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies
(Elsevier, 2016-05-20)
Background Several studies reported a U-shaped association between urinary sodium excretion and cardiovascular disease events and mortality. Whether these associations vary between those individuals with and without ...
How robust is the evidence for recommending very low salt intake in entire populations?
(Elsevier, 2016-10-03)
[No abstract available]
Integrated in vitro and in silico modelling delineates the molecular effects of a synbiotic regimen on colorectal cancer-derived cells
(Cell Press, 2019-04-30)
By modulating the human gut microbiome, prebiotics and probiotics (combinations of which are called synbiotics) may be used to treat diseases such as colorectal cancer (CRC). Methodological limitations have prevented ...
Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study
(BMJ Publishing Group, 2019-03-13)
Abstract
Objective To evaluate the joint association of sodium and potassium urinary excretion (as surrogate measures of intake) with cardiovascular events and mortality, in the context of current World Health Organization ...
Dietary sodium and cardiovascular disease risk
(Massachusetts Medical Society, 2016-12-15)
[No abstract available]