Now showing items 1-5 of 5
The association of white matter volume in psychotic disorders with genotypic variation in NRG1, MOG and CNP: a voxel-based analysis in affected individuals and their unaffected relatives
(Nature Publishing Group, 2012)
We investigated the role of variation in putative psychosis genes coding for elements of the white matter system by examining the contribution of genotypic variation in three single-nucleotide polymorphisms (SNPs) neuregulin ...
Gender-specific abnormalities in the serotonin transporter system in panic disorder
(Cambridge University Press, 2013)
The central serotonergic system has been implicated in the pathophysiology of panic disorder (PD) by evidence of abnormally elevated serotonin-turnover, reduced pre- and post-synaptic 5-HT(1A-)receptor sensitivity and ...
Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [C-11]DASB
In a previous study we showed that genetic variation in HTR2A, which encodes the serotonin 2A receptor, influenced outcome of citalopram treatment in patients with major depressive disorder. Since chronic administration ...
The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy
Objective: To study 5-HT transport and 5-HT1A receptors in temporal lobe epilepsy (TLE) and depression.Methods: Thirteen patients had PET with [C-11]DASB for 5-HTT and [F-18]FCWAY for 5-HT1A receptor binding, MRI, and ...
Distribution of tract deficits in schizophrenia
(BioMed Central, 2014-04-02)
Background: Gray and white matter brain changes have been found in schizophrenia but the anatomical organizing process underlying these changes remains unknown. We aimed to identify gray and white matter volumetric changes ...