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Now showing items 191-200 of 202
Supporting parents caring for a child with a learning disability
(RCN Publishing, 2007-12-12)
Parenting a child with a learning disability is a unique and often demanding experience. The learning disability nurse can play a key role in supporting parents and families by communicating effectively, providing information ...
Increasing the uptake of cervical screening programmes
(Mark Allen Healthcare, 2008)
Successful cervical screening programmes depend on the degree of coverage and the rate of attendance. There are many demographic reasons why some women fail to attend for cervical screening, including lack of knowledge and ...
Patient rehabilitation following lower limb amputation
(RCN Publishing, 2008-08-13)
Patient rehabilitation following lower limb amputation is essential to provide optimum patient outcomes and to improve the amputee’s quality of life. The age of the patient and the stump length or level of amputation emerge ...
Modulation of stress by imidazoline binding sites: Implications for psychiatric disorders
(Taylor & Francis, 2009-07-07)
In this review, we present evidence for the involvement of imidazoline binding sites (IBS) in modulating responses to stress, through central control of monoaminergic and hypothalamo-pituitary-adrenal (HPA) axis activity. ...
Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia
(Bentham Science Publishers, 2007)
The endogenous polyamines (spermine, spermidine, and putrescine) are present at relatively high concentrations in the mammalian brain and play crucial roles in a variety of aspects of cell functioning. Stroke is the third ...
A review of the international literature on health promotion competencies: identifying frameworks and core competencies.
(SAGE Journals Online, 2009-05-15)
Building a competent health promotion workforce with the necessary knowledge and skills to develop, implement and evaluate health promotion policies and practice is fundamental to mainstreaming and sustaining health promotion ...
Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: Opioid receptor dependency and molecular correlates
(International Association for the Study of Pain, 2008-12)
The opioid and endocannabinoid systems mediate analgesia expressed upon re-exposure to a contextually aversive stimulus (fear-conditioned analgesia; FCA), and modulate the mitogen-activated protein kinase (MAPK) pathway. ...
Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats
(Elsevier, 2003-07-31)
The analgesic potential of cannabinoids may be hampered by their ability to produce aversive emotion when administered systemically. We investigated the hypothesis that the midbrain periaqueductal grey (PAG) is a common ...
Evidence for differential modulation of conditioned aversion and fear‐conditioned analgesia by CB1 receptors
(Wiley, 2004-07-15)
Fear‐conditioned analgesia is an important survival response mediated by substrates controlling nociception and aversion. Cannabinoid1 (CB1) receptors play an important role in nociception and aversion. However, their role ...