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Genotype-dependent responsivity to inflammatory pain: A role for TRPV1 in the periaqueductal grey
(Elsevier, 2016-08-09)
Negative affective state has a significant impact on pain, and genetic background is an important moderating influence on this interaction. The Wistar-Kyoto (WKY) inbred rat strain exhibits a stress-hyperresponsive, ...
Sex differences and similarities in depressive-and anxiety-like behaviour in the Wistar-Kyoto rat
(Elsevier, 2016-08-31)
Depression is a debilitating psychiatric disorder that is highly comorbid with anxiety. Depression is twice as prevalent in women as in men, however, females remain underrepresented in preclinical research. The stress ...