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A systematic review of measurement tools for the proactive assessment of patient safety in general practice
(Lippincott, Williams & Wilkins, 2017-04-04)
Background
Primary care physicians have reported a difficulty in understanding how best to measure and improve patient safety in their practices.
Objectives
The aims of the study were to identify measures of patient ...
A mixed method, multiperspective evaluation of a near peer teaching programme
(BMJ Publishing Group, 2017-02-24)
Purpose of study Peer teaching (PT) has become increasingly popular. PT may offer benefits for students, tutors and institutions. Although resistance to PT has been identified among faculty, research has typically focused ...
A mixed methods evaluation of paediatric trainee preparedness to manage cardiopulmonary arrests
(Springer, 2017-09-21)
Paediatric cardiopulmonary arrest (CPA) survival rates are strongly linked to the training of the doctors responding to the event. This study sought to characterise the level of experience in managing CPAs among paediatric ...
Interventions to improve hand hygiene compliance in the ICU: A systematic review
(Lippincott, Williams & Wilkins, 2017-11)
Objectives:
To synthesize the literature describing interventions to improve hand hygiene in ICUs, to evaluate the quality of the extant research, and to outline the type, and efficacy, of interventions described.
Data ...
Don't blame it all on antibodies--The need for exhaustive characterisation, appropriate handling, and addressing the issues that affect specificity
(Elsevier, 2017-01-30)
Recently there have been numerous very thought-provoking reports describing many issues relating to the overall quality of antibodies that are currently available. It appears that multiple major clinical and other analytical ...
The management of diabetes in adults and children with psychiatric disorders in inpatient settings
(JBDS-IP (Joint British Diabetes Societies for Inpatient Care) and RCPsych (Royal College of Psychiatrists), 2017-05)
Nearly every category of ICD-10 Chapter F (mental disorders) is associated with diabetes and with
worse outcomes and premature mortality.1
In addition, many people with diabetes suffer from diabetes
related distress.
The ...
Animal models of focal cerebral ischaemia and haemorrhage transformation: considerations in experimental stroke study design
(Bentham Science Publishers, 2017)
Background: Ischaemic stroke is often complicated with haemorrhage within the infarct zone or in a remote location especially when treated with intravenous thrombolysis and/or thrombectomy. While these early recanalisation ...
Pharmacological inhibition of FAAH modulates TLR-induced neuroinflammation, but not sickness behaviour: An effect partially mediated by central TRPV1
(Elsevier, 2017-02-22)
Aberrant activation of toll-like receptors (TLRs), key components of the innate immune system, has been proposed to underlie and exacerbate a range of central nervous system disorders. Increasing evidence supports a role ...
FAAH, but not MAGL, inhibition modulates acute TLR3‐induced neuroimmune signaling in the rat, independent of sex
(Wiley, 2017-07-20)
Toll-like receptor (TLR)3 is a key component of the innate immune response to viral infection. The present study firstly examined whether sex differences exist in TLR3-induced inflammatory, endocrine, and sickness responses. ...
Dose-dependent effects of binge-like methamphetamine dosing on dopamine and neurotrophin levels in rat brain
(Karger Publishers, 2017-10-24)
This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetamine treatments on the regional expression of neurotrophin proteins in the brain and serum 2 h after the last dose, in ...