Search
Now showing items 41-50 of 56
Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury
(Elsevier, 2018-09-26)
Background: The use of animals to model spinal cord injury (SCI) requires extensive post-operative care and can be expensive, which makes an altemative model extremely attractive. The use ofex vivo slice cultures is an ...
PPARs and pain
(Wiley, 2018-04-21)
Chronic pain is a common cause of disability worldwide and remains a global health and socio-economic challenge. Current analgesics are either ineffective in a significant proportion of patients with chronic pain or ...
Resource allocation and rationing in nursing care: A discussion paper
(SAGE Publications, 2018-04-01)
Driven by interests in workforce planning and patient safety, a growing body of literature has begun to identify the reality and the prevalence of missed nursing care, also specified as care left undone, rationed care or ...
A systematic review of interventions to foster physician resilience
(BMJ Publishing Group, 2018-02-21)
This review aimed to synthesise the literature describing interventions to improve resilience among physicians, to evaluate the quality of this research and to outline the type and efficacy of interventions implemented. ...
The 100 most cited articles on healthcare simulation: a bibliometric review
(Lippincott, Williams & Wilkins, 2018-06)
This article provides an overview and synthesis of the 100 most cited healthcare simulation publications to provide insight into the articles that have shaped current knowledge and practice. Searches of the Scopus and Web ...
Love and dating patterns for same‐ and both‐gender attracted adolescents across Europe
(Wiley, 2018-04-15)
Sexual orientation is a multidimensional phenomenon, which includes identity, behavior, and attraction. The attraction component, however, is less studied than the other two. In this article, we present the development of ...
Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
(BMC (part of Springer Nature), 2018-04-10)
Background
Stromal gene expression patterns predict patient outcomes in colorectal cancer. TRIM28 is a transcriptional co-repressor that regulates an abundance of genes through the KRAB domain family of transcription ...
Effect of a binge-like dosing regimen of methamphetamine on dopamine levels and tyrosine hydroxylase expressing neurons in the rat brain
(Elsevier, 2018-10-05)
Methamphetamine, an amphetamine derivative, is a powerful psychomotor stimulant and commonly used drug of abuse. This study examined the effect of binge-like methamphetamine (MA) dosing (4 x 4 mg/kg, s.c., 2 h apart) on ...
Ulk4 regulates GABAergic signaling and anxiety-related behavior
(Springer Nature, 2018-02-02)
Excitation/inhibition imbalance has been proposed as a fundamental mechanism in the pathogenesis of neuropsychiatric and neurodevelopmental disorders, in which copy number variations of the Unc-51 like kinase 4 (ULK4) gene ...
FAAH inhibition attenuates TLR3-mediated hyperthermia, nociceptive- and anxiety-like behaviour in female rats
(Elsevier, 2018-06-25)
Aberrant activation of toll-like receptor (TLR)s results in persistent and prolonged neuroinflammation and has been implicated in the pathogenesis and exacerbation of psychiatric and neurodegenerative disorders. TLR3 ...