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TNF-a/IL-1ß-licensed mesenchymal stromal cells promote corneal allograft survival via myeloid cell-mediated induction of Foxp3+ regulatory T cells in the lung.
(Federation of American Society of Experimental Biology (FASEB), 2019-05-20)
Mesenchymal stromal cells (MSCs) have shown promise as a therapy for immune-mediated disorders, including transplant rejection. Our group previously demonstrated the efficacy of pretransplant, systemic administration of ...
Oral loratadine in the management of G-CSF induced bone pain: a pilot study
(Mark Allen Healthcare, 2019-02-27)
This pilot study aimed to ascertain if bone pain induced by granulocyte-colony stimulating factors (G-CSFs) can be alleviated or eliminated by oral antihistamine loratadine. Twelve patients with cancer receiving chemotherapy ...
A systematic review and narrative synthesis of occupational therapy-led interventions for individuals with anxiety and stress-related disorders
(Taylor & Francis, 2019-01-15)
Anxiety and stress-related disorders are highly prevalent and impede participation in life activities. Occupational therapists work extensively with people diagnosed with these disorders but the effectiveness of their ...
Lipid lowering therapy, low-density lipoprotein level and risk of intracerebral hemorrhage – a meta-analysis
(Elsevier, 2019-03-14)
The association of lipid lowering therapy and intracerebral hemorrhage risk is controversial.
We performed a cumulative meta-analysis of lipid lowering trials that reported intracerebral hemorrhage. Statin, fibrate, ...
Hypoxia activates the PTHrP-MEF2C pathway to attenuate hypertrophy in mesenchymal stem cell derived cartilage
(Nature Research, 2019-09-16)
Articular cartilage lacks an intrinsic repair capacity and due to the ability of mesenchymal stem cells (MSCs) to differentiate into chondrocytes, MSCs have been touted as a cellular source to regenerate damaged cartilage. ...
Diabetes mellitus and gender have a negative impact on the outcome of hip fracture surgery – a pilot study
(Wiley, 2019-11-07)
Diabetes mellitus (DM) is associated with an elevated risk of post-operative complications. The impact it has on patients living with DM following hip fracture surgery (HFS) is not completely understood, and may represent ...
Balancing perspectives on intervention feasibility: using stakeholder views in decision-making
(BMJ Publishing Group, 2019-03-20)
Background Anxiety and stress are prevalent in general practice and primary care settings, particularly among women. The ‘Redesigning Daily Occupations’ (ReDO) programme is a manualised occupational therapy-led intervention ...
Telling a ‘good or white lie’: The views of people living with dementia and their carers
(SAGE Publications, 2019-02-25)
Objective: A common symptom of cognitive decline in people living with dementia, or people
with memory problems, the cause of which has not yet been diagnosed, is the person repeatedly
asking for loved ones who are ...
Critical care nurses experiences of providing care for adults in a highly technological environment: A qualitative evidence synthesis
(Wiley, 2019-08-20)
Abstract
Aims
To synthesise the available body of qualitative evidence relating to nurses' perceptions and experiences of care provision in adult critical care environments.
Methods
The study adhered to ENTREQ ...
The role of religion in buffering the impact of stressful life events on depressive symptoms in patients with depressive episodes or adjustment disorder.
(MDPI, 2019-04-08)
Most studies into the role of religiousness in relation to depression severity have mainly found an inverse relationship between greater religiousness and lower levels of depressive symptoms. There is reason to assume that ...