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    AuthorFinn, David P. (18)Roche, Michelle (12)Rea, Kieran (4)Butler, Ryan K. (3)Ford, Gemma K. (3)... View MoreSubject
    Pain (19)
    Fear (5)Analgesia (4)Periaqueductal grey (4)Rat (4)... View MoreDate Issued2010 - 2020 (16)2003 - 2009 (3)TypeArticle (17)Book chapter (2)

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    Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala 

    Burke, Nikita N.; Geoghegan, E.; Moriarty, Orla; Finn, David P.; Kerr, Daniel M.; Roche, Michelle (Wiley, 2013-08-29)
    The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ...
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    Neuroinflammatory mechanisms linking pain and depression 

    Burke, Nikita N.; Finn, David P.; Roche, Michelle (Karger, 2015)
    Depression and chronic pain have been estimated to co-occur in up to 80% of patients suffering from these disorders, with this co-morbidity being more disabling and more expensive to both patients and society than either ...
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    Stress-induced analgesia. 

    Butler, Ryan K.; Finn, David P. (Butler, R. K. & Finn, D.P. (2009). Stress-induced analgesia. Progress in Neurobiology, 88, 184-202., 2009)
    For over 30 years, scientists have been investigating the phenomenon of pain suppression upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress-induced analgesia. These studies have ...
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    Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate 

    Rea, Kieran; Roche, Michelle; Finn, David P. (2007)
    Recent physiological, pharmacological and anatomical studies provide evidence that one of the main roles of the endocannabinoid system in the brain is the regulation of ¿-aminobutyric acid (GABA) and glutamate release. ...
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    The effect of pain on cognitive function: a review of clinical and preclinical research. 

    Moriarty, Orla; McGuire, Brian E.; Finn, David P. (2011)
    Cognitive impairment is commonly associated with the pain experience. This impairment represents a major obstacle to daily activities and rehabilitation, especially in the chronic pain population. Here we review clinical ...
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    Lived experiences of fibromyalgia 

    Diviney, Martina; Dowling, Maura (RCN Publishing, 2015-02-10)
    Martina Diviney and Maura Dowling explain why this chronic illness can take a long time to diagnose and how assessment tools can be used to speed up the process This phenomenological study explored the lived experience ...
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    A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats. 

    Ford, Gemma K.; Kieran, Siobhan; Dolan, Kenneth; Harhen, Brendan; Finn, David P. (Elsevier, 2011-08)
    The endogenous cannabinoid (endocannabinoid) system plays an important role in fear-conditioned analgesia (FCA) and expression and extinction of conditioned fear. The hippocampus has an established role in both pain and ...
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    The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nocicpetive tone 

    Olango, W.M.; Roche, Michelle; Ford, Gemma K.; Harhen, Brendan; Finn, David P. (Wiley, 2011)
    Background and purpose: Endocannabinoids in the midbrain periaqueductal grey (PAG) are involved in modulating nociception and unconditioned stress-induced analgesia, however, their role in fear-conditioned analgesia (FCA) ...
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    Fear-induced suppression of nociceptive behaviour and activation of signal transduction molecules in the rat periaqueductal grey: role of fatty acid amide hydrolase. 

    Butler, Ryan K.; Ford, Gemma K.; Hogan, Michelle; Roche, Michelle; Doyle, Karen M.; Kelly, John P.; Finn, David P. (Sage, 2011-09-17)
    The endocannabinoid system regulates nociception and aversion and mediates fear-conditioned analgesia (FCA). We investigated the effects of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which inhibits the catabolism ...
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    Molecular and electrophysiological changes in the prefrontal cortex-amygdala-dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned analgesia 

    Butler, Ryan K.; Finn, David P. (Elsevier, 2011-10)
    Fear-conditioned analgesia (FCA) is the reduction in pain responding which is expressed upon re-exposure to a context previously paired with an aversive stimulus. Projections along the prefrontal cortex (PFC)¿amygdala¿dorsal ...
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