• Login
    ARAN - Access to Research at NUI Galway
    Search 
    •   ARAN Home
    • College of Medicine, Nursing and Health Sciences
    • Search
    •   ARAN Home
    • College of Medicine, Nursing and Health Sciences
    • Search
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ARANCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsTypesThis CommunityBy Issue DateAuthorsTitlesSubjectsTypes

    My Account

    LoginRegister

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Help

    How to submit and FAQs

    Discover

    Author
    Roche, Michelle (61)
    Finn, David P. (49)Kerr, Daniel M. (12)Burke, Nikita N. (9)Kelly, John P. (9)... View MoreSubjectPain (12)Depression (8)Anandamide (6)Endocannabinoid (6)2-AG (5)... View MoreDate Issued2020 - 2021 (10)2010 - 2019 (47)2003 - 2009 (4)TypeArticle (55)Book chapter (5)Conference Paper (1)

    Search

    Show Advanced FiltersHide Advanced Filters

    Filters

    Use filters to refine the search results.

    Now showing items 1-10 of 61

    • Sort Options:
    • Relevance
    • Title Asc
    • Title Desc
    • Issue Date Asc
    • Issue Date Desc
    • Results Per Page:
    • 5
    • 10
    • 20
    • 40
    • 60
    • 80
    • 100
    Thumbnail

    Maternal deprivation is associated with sex-dependent alterations in nociceptive behavior and neuroinflammatory mediators in the rat following peripheral nerve injury 

    Burke, Nikita N.; Llorente, Ricardo; Marco, Eva M.; Tong, Kezanne; Finn, David P.; Viveros, Maria-Paz; Roche, Michelle (Elsevier, 2013-10)
    Early-life stress is associated with an increased risk of developing affective disorders and chronic pain conditions. This study examined the effect of maternal deprivation (MD) on nociceptive responding prior to and ...
    Thumbnail

    Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala 

    Burke, Nikita N.; Geoghegan, E.; Moriarty, Orla; Finn, David P.; Kerr, Daniel M.; Roche, Michelle (Wiley, 2013-08-29)
    The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ...
    Thumbnail

    Circuitry underlying regulation of the serotonergic system by swim stress 

    Roche, Michelle; Commons, Kathryn G.; Peoples, Andrew; Valentino, Rita J. (Society for Neuroscience, 2003-02-01)
    The dorsal raphe nucleus (DR)–serotonin (5-HT) system has been implicated in depression and is dramatically affected by swim stress, an animal model with predictive value for antidepressants. Accumulating evidence implicates ...
    Thumbnail

    Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype 

    Burke, Nikita N.; Finn, David P.; Roche, Michelle (Elsevier, 2015-02)
    Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating ...
    Thumbnail

    Neuroinflammatory mechanisms linking pain and depression 

    Burke, Nikita N.; Finn, David P.; Roche, Michelle (Karger, 2015)
    Depression and chronic pain have been estimated to co-occur in up to 80% of patients suffering from these disorders, with this co-morbidity being more disabling and more expensive to both patients and society than either ...
    Thumbnail

    Anandamide modulation of endotoxin-induced inflammation 

    Kerr, Daniel M.; Henry, Rebecca; Roche, Michelle (OMICS International, 2013-12-20)
    The endocannabinoid system is comprised of the CB1 and CB2 receptors, the naturally occurring endogenous ligands, anandamide (AEA) and 2-arachidonyl glycerol (2-AG); and the enzymes involved in their synthesis and ...
    Thumbnail

    Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate 

    Rea, Kieran; Roche, Michelle; Finn, David P. (2007)
    Recent physiological, pharmacological and anatomical studies provide evidence that one of the main roles of the endocannabinoid system in the brain is the regulation of ¿-aminobutyric acid (GABA) and glutamate release. ...
    Thumbnail

    Pharmacological inhibition of monoacylglycerol lipase attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action 

    Kerr, Danny; Harhen, Brendan; Egan, Jonathan; Finn, David P.; Roche, Michelle (2013)
    Background and purpose: This study determined the effect of JZL184, a selective inhibitor of monoacylglycerol lipase (MAGL), the enzyme which preferentially catabolises the endocannabinoid 2-arachidonoyl glycerol (2-AG), ...
    Thumbnail

    The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nocicpetive tone 

    Olango, W.M.; Roche, Michelle; Ford, Gemma K.; Harhen, Brendan; Finn, David P. (Wiley, 2011)
    Background and purpose: Endocannabinoids in the midbrain periaqueductal grey (PAG) are involved in modulating nociception and unconditioned stress-induced analgesia, however, their role in fear-conditioned analgesia (FCA) ...
    Thumbnail

    Fear-induced suppression of nociceptive behaviour and activation of signal transduction molecules in the rat periaqueductal grey: role of fatty acid amide hydrolase. 

    Butler, Ryan K.; Ford, Gemma K.; Hogan, Michelle; Roche, Michelle; Doyle, Karen M.; Kelly, John P.; Finn, David P. (Sage, 2011-09-17)
    The endocannabinoid system regulates nociception and aversion and mediates fear-conditioned analgesia (FCA). We investigated the effects of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which inhibits the catabolism ...
    • 1
    • 2
    • 3
    • 4
    • . . .
    • 7
    • Copyright @ NUI Galway 2016
    • Library
    • NUI Galway