Now showing items 1-6 of 6
Cognition and pain
(Lippincott, Williams & Wilkins, 2014-06)
Purpose of reviewPain and cognition share common neural substrates and are known to interact reciprocally. This has implications for treatment and management of pain conditions; pain can negatively affect cognitive ...
Oral loratadine in the management of G-CSF induced bone pain: a pilot study
(Mark Allen Healthcare, 2019-02-27)
This pilot study aimed to ascertain if bone pain induced by granulocyte-colony stimulating factors (G-CSFs) can be alleviated or eliminated by oral antihistamine loratadine. Twelve patients with cancer receiving chemotherapy ...
The prefrontal cortical endocannabinoid system modulates fear–pain interactions in a subregion‐specific manner
Background and Purpose The emotional processing and coordination of top‐down responses to noxious and conditioned aversive stimuli involves the medial prefrontal cortex (mPFC). Evidence suggests that subregions of the ...
High times for painful blues: the endocannabinoid system in pain-depression comorbidity
(Oxford University Press (OUP), 2015-09-05)
Depression and pain are two of the most debilitating disorders worldwide and have an estimated cooccurrence of up to 80%. Comorbidity of these disorders is more difficult to treat, associated with significant disability ...
Evidence for differential modulation of conditioned aversion and fear‐conditioned analgesia by CB1 receptors
Fear‐conditioned analgesia is an important survival response mediated by substrates controlling nociception and aversion. Cannabinoid1 (CB1) receptors play an important role in nociception and aversion. However, their role ...
Antinociceptive effects of the GPR55 Antagonist CID16020046 injected into the rat anterior cingulate cortex
The G-protein coupled receptor, GPR55, modulates nociceptive processing. Given the expression of GPR55 in the anterior cingulate cortex (ACC), a key brain region involved in the cognitive and affective dimensions of pain, ...