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Cell viability in three ex vivo rat models of spinal cord injury
(Wiley, 2018-11-11)
Spinal cord injury (SCI) is a devastating disorder that has a poor prognosis of recovery. Animal models of SCI are useful to understand the pathophysiology of SCI and the potential use of therapeutic strategies for human ...
Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury
(Elsevier, 2018-09-26)
Background: The use of animals to model spinal cord injury (SCI) requires extensive post-operative care and can be expensive, which makes an altemative model extremely attractive. The use ofex vivo slice cultures is an ...
Therapeutic effect of neurotrophin-3 treatment in an injectable collagen scaffold following rat spinal cord hemisection injury
(American Chemical Society, 2016-08-01)
Spinal cord injury (SCI) patients display varying quantities of spinal cord tissue damage with injuries that present as complete, incomplete or compressive. One theory proposed to repair the injured spinal cord and regain ...