Now showing items 1-13 of 13

    • 6-iodonordihydrocapsaicin 

      Roche, Michelle; Finn, David P. (2009)
      6-Iodonordihydrocapsaicin was first synthesized by Giovanni Appendino at the Department of Chemical, Food, Pharmaceutical and Pharmacological Sciences (DiSCAFF), Novara, Italy, while developing a series of halogenated ...
    • Cannabinoids and pain: sites and mechanisms of action 

      Starowicz, Katarzyna; Finn, David P. (Elsevier, 2017-06-20)
      The endocannabinoid system, consisting of the cannabinoid(1) receptor (CB1R) and cannabinoid(2) receptor (CB2R), endogenous cannabinoid ligands (endocannabinoids), and metabolizing enzymes, is present throughout the pain ...
    • Circulating MicroRNAs in cancer 

      O’Brien, Killian P.; Ramphul, Eimear; Howard, Linda; Gallagher, William M.; Malone, Carmel; Kerin, Michael J.; Dwyer, Róisín M. (Humana Press, 2016-11-09)
      It is believed that microRNAs have potential as circulating biomarkers of disease, however successful clinical implementation remains a challenge. This chapter highlights broad variations in approaches to microRNA analysis ...
    • Curriculum development for sustainable civic engagement 

      Boland, Josephine (Educational Developers of Ireland Network, 2013)
      Capacity building both for students and for community partners is an explicit goal for one particular teaching and learning innovation in Irish higher education. In addition to offering the opportunity to apply ...
    • Diagnostic and therapeutic mesenchymal stem cells for breast cancer treatment 

      Dwyer, Róisín M. (Wiley, 2013-08-09)
      [No abstract available]
    • Exploring gender and power in clinical encounters 

      O'Malley, Mary Pat (London: Psychology Press, 2011)
      [No abstract available]
    • L2 acquisition of verbal constructions: Expressing motion in L2 French and English 

      Antonijevic, Stanislava; Berthaud, Sarah (John Benjamins, 2012)
      The study examines the production of sentences describing motion in L2 learners, focusing on progress in learning verbal constructions, i.e. pairings of verbs of motion and their compatible syntactic frames in English and ...
    • Neuroinflammatory mechanisms linking pain and depression 

      Burke, Nikita N.; Finn, David P.; Roche, Michelle (Karger, 2015)
      Depression and chronic pain have been estimated to co-occur in up to 80% of patients suffering from these disorders, with this co-morbidity being more disabling and more expensive to both patients and society than either ...
    • The Olfactory Bulbectomised Mouse 

      Roche, Michelle (Humana Press, 2011)
      [no abstract available]
    • The role of the brain's endocannabinoid system in pain and its modulation by stress 

      Corcoran, Louise; Roche, Michelle; Finn, David P. (Elsevier, 2015-11-06)
      Stress has a complex, bidirectional modulatory influence on pain. Stress may either reduce (stress-induced analgesia) or exacerbate (stress-induced hyperalgesia) pain depending on the nature, duration, and intensity of the ...
    • Signaling pathways in mouse embryo stem cell self-renewal 

      Quinlan, Leo (In Tech, 2011)
      At the pre-implantation blastocyst stage of development, the mammalian embryo is composed of a unique collection of cells of which three major populations predominate. The outermost layer the trophectoderm (TE) gives ...
    • Supraspinal transient receptor potential subfamily V member 1 (TRPV1) in pain and psychiatric disorders 

      Madasu, M.K.; Roche, Michelle; Finn, David P. (Karger, 2015)
      The transient receptor potential subfamily V member 1 (TRPV1) belongs to the diverse transient receptor potential (TRP) family of cation channels. It was first characterized in primary afferent fibres as a receptor for ...
    • A wicked problem and the SIMPle Solution 

      Duane, Sinead; Domegan, Christine; Callan, Aoife; Galvin, Sandra; Cormican, Martin; Bennett, Kathleen; Murphy, Andrew W.; Vellinga, Akke (Routledge, 2017-11-02)
      [No abstract available]