Browsing Externally hosted open access publications with University of Galway authors (1) by Subject "death receptor"
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Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the dr5 receptor
(Proceedings of the National Academy of Sciences, 2006-05-26)Tumor necrosis factor-related apoptosis-inclucing ligand (TRAIL) is a potential anticancer drug that selectively induces apoptosis in a variety of cancer cells by interacting with death receptors DR4 and DR5. TRAIL can ...