Browsing School of Physics (Conference Papers) by Author "http://dx.doi.org/10.13039/501100007601"
Now showing items 1-2 of 2
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Label free ultra-sensitive imaging with sub-diffraction spatial resolution
Alexandrov, Sergey; Das, Nandan; McGrath, James; Owens, Peter; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Leahy, Martin (IEEE, 2019-07-09)In this paper, we show a new way to break the resolution limit and dramatically improve sensitivity to structural changes. To realize it we developed a novel label free contrast mechanism, based on the spectral encoding ... -
Ultra-sensitive label free imaging below the resolution limit
Alexandrov, Sergey; McGrath, James; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Hogan, Josh; Leahy, James J. (SPIE (Society of Photo-optical Instrumentation Engineers) Digital Library, 2019-02-02)Almost all known nanoscopy methods rely upon the contrast created by fluorescent labels attached to the object of interest. This causes limitations on their applicability to in vivo imaging. A new label-free spectral ...