Show simple item record

dc.contributor.authorTandan, Meera
dc.contributor.authorDuane, Sinead
dc.contributor.authorCormican, Martin
dc.contributor.authorMurphy, Andrew W.
dc.contributor.authorVellinga, Akke
dc.date.accessioned2017-06-28T08:00:08Z
dc.date.available2017-06-28T08:00:08Z
dc.date.issued2016-09-15
dc.identifier.citationTandan, Meera, Duane, Sinead, Cormican, Martin, Murphy, Andrew, & Vellinga, Akke. (2016). Reconsultation and Antimicrobial Treatment of Urinary Tract Infection in Male and Female Patients in General Practice. Antibiotics, 5(3), 31. DOI: 10.3390/antibiotics5030031en_IE
dc.identifier.issn2079-6382
dc.identifier.urihttp://hdl.handle.net/10379/6609
dc.description.abstractCurrent antimicrobial prescribing guidelines indicate that male and female patients with urinary tract infections (UTIs) should be treated with same antimicrobials but for different durations. The aim of this study was to explore the differences in reconsultations and antimicrobial prescribing for UTI for both males and females. A total of 2557 adult suspected UTI patients participating in the Supporting the Improvement and Management of Prescribing for urinary tract infection (SIMPle) study from 30 general practices were analyzed. An antimicrobial was prescribed significantly more often to females (77%) than males (63%). Nitrofurantoin was prescribed more often for females and less often for males (58% vs. 41%), while fluoroquinolones were more often prescribed for males (11% vs. 3%). Overall, reconsultation was 1.4 times higher in females, and if the antimicrobial prescribed was not the recommended first-line (nitrofurantoin), reconsultation after empirical prescribing was significantly higher. However, the reconsultation was similar for males and females if the antimicrobial prescribed was first-line. When a urine culture was obtained, a positive culture was the most important predictor of reconsultation (Odds ratio 1.8 (95% CI 1.3-2.5)). This suggests, when prescribing empirically, that male and female UTI patients should initially be treated with first-line antimicrobials (nitrofurantoin) with different durations (50-100 mg four times daily for three days in females and seven days for males). However, the consideration of a culture test before prescribing antimicrobials may improve outcomes.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherMDPI (Multidisciplinary Digital Publishing Institute)en_IE
dc.relation.ispartofAntibiotics-Baselen
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectUrinary tract infectionen_IE
dc.subjectReconsultationen_IE
dc.subjectGeneral practiceen_IE
dc.subjectAntimicrobial prescribingen_IE
dc.subjectTreatmenten_IE
dc.subjectCulture testen_IE
dc.subjectMaleen_IE
dc.subjectFemaleen_IE
dc.subjectAcute uncomplicated cystitisen_IE
dc.titleReconsultation and antimicrobial treatment of urinary tract infection in male and female patients in general practiceen_IE
dc.typeArticleen_IE
dc.date.updated2017-06-16T07:06:50Z
dc.identifier.doi10.3390/antibiotics5030031
dc.local.publishedsourcehttp://dx.doi.org/10.3390/antibiotics5030031en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|
dc.internal.rssid12073151
dc.local.contactAkke Vellinga, General Practice/Bacteriology, Nui Galway. 5192 Email: akke.vellinga@nuigalway.ie
dc.local.copyrightcheckedNo
dc.local.versionACCEPTED
nui.item.downloads326


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland