Browsing Biomedical Engineering (Scholarly Articles) by Title
Now showing items 46-65 of 128
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The evolution of Ireland’s medical device cluster and its future direction
(MDPI, 2022-08-16)Ireland has developed a highly successful medical device cluster. Most of the industry started from USA multinationals that moved to Ireland in the 1990s. An ecosystem has now developed with strong linkages between ... -
An experimental and computational investigation of the post-yield behaviour of trabecular bone during vertebral device subsidence
(Springer-Verlag, 2013)Interbody fusion device subsidence has been reported clinically. An enhanced understanding of the mechanical behaviour of the surrounding bone would allow for accurate predictions of vertebral subsidence. The multiaxial ... -
Experimental and computational investigation of the role of stress fiber contractility in the resistance of osteoblasts to compression
(2013)The mechanical behavior of the actin cytoskeleton has previously been investigated using both experimental and computational techniques. However, these investigations have not elucidated the role the cytoskeleton plays in ... -
Experimental and numerical characterisation of the elasto-plastic properties of bovine trabecular bone and a trabecular bone analogue
(2012)The inelastic pressure dependent compressive behaviour of bovine trabecular bone is investigated through experimental and computational analysis. Two loading configurations are implemented, uniaxial and confined compression, ... -
Experimental mechanical testing of Poly (l-Lactide) (PLLA) to facilitate pre-degradation characteristics for application in cardiovascular stenting
(Elsevier, 2016-07-19)Next-generation stents made from Biodegradable Polymers (BPs) aim to address the long-term risks (i.e. late restenosis and in-stent thrombosis) associated with both Bare Metal Stents and Drug Eluting Stents, whilst aiming ... -
An exploration of organizational readiness factors for Quality 4.0: an intercontinental study and future research directions
(Emerald, 2021-12-31)Quality 4.0 incorporates the role of automation and digitization and provides competitive advantage for organizations by enhancing customer experience and increase profitability. The purpose of this study is to critically ... -
Exploring the use of operational excellence methodologies in the era of COVID-19: perspectives from leading academics and practitioners
(Emerald, 2021-02-25)Purpose This paper aims to present the results of a study carried out by the authors in the form of research interviews on the topic: “Exploring the use of operational excellence methodologies in the era of COVID-19.” ... -
Fabrication, mechanical and in vivo performance of polycaprolactone/tricalcium phosphate composite scaffolds
(2012)This paper explores the use of selective laser sintering (SLS) for the generation of bone tissue engineering scaffolds from polycaprolactone (PCL) and PCL/tricalcium phosphate (TCP). Different scaffold designs are generated, ... -
Fluid flow in the osteocyte mechanical environment: a fluid-structure interaction approach
(Springer Verlag, 2013-04-09)Osteocytes are believed to be the primary sensor of mechanical stimuli in bone, which orchestrate osteoblasts and osteoclasts to adapt bone structure and composition to meet physiological loading demands. Experimental ... -
A Fluorescently Labeled, Hyperbranched Polymer Synthesized from DE-ATRP for the Detection of DNA Hybridization
(Royal Society of Chemistry, 2012-01)The early detection of oligonucleotide biomarkers of disease, such as microRNAs, has been established as a fundamental factor in cancer diagnosis. As the levels of these small molecules (microRNAs) in blood have recently ... -
How do the technological capability and strategic flexibility of an organization impact its successful implementation of Industry 4.0? A qualitative viewpoint
(Emerald, 2022-04-18)Purpose Industry 4.0 (I 4.0) consists of numerous digital technologies applied in organizations strategically to add value to the customer. Different organizations have varying degrees of technological capability and ... -
How does performance vary between early and late adopters of Industry 4.0? A qualitative viewpoint
(Emerald, 2021-10-12)Purpose Industry 4.0 is a new trend among organizations. Some organizations have been early adopters or later adopters of Industry 4.0. The purpose of this paper is to investigate how performance effects vary between early ... -
Hyperbranched PEGmethacrylate linear pDMAEMA block copolymer as an efficient non-viral gene delivery vector
(Elsevier, 2012-06-02)A unique hyperbranched polymeric system with a linear poly-2-dimethylaminoethyl methacrylate (pDMAEMA) block and a hyperbranched polyethylene glycol methyl ether methacrylate (PEGMEMA) and ethylene dimethacrylate (EGDMA) ... -
The impact of Healthcare 4.0 on the healthcare service quality: A systematic literature review
(Taylor & Francis, 2022-03-24)Healthcare 4.0 is inspired by Industry 4.0 and its application has resulted in a paradigmatic shift in the field of healthcare. However, the impact of this digital revolution in the healthcare system on healthcare service ... -
The impact of Industry 4.0 on the medical device regulatory product life cycle compliance
(MDPI, 2022-11-07)The fourth industrial revolution, also referred to as Industry 4.0, has resulted in many changes within the MedTech Industry. The MedTech industry is changing from interconnected manufacturing systems using cyber-physical ... -
The impact of medical cyber–physical systems on healthcare service delivery
(Emerald, 2022-04-12)Purpose The pandemic has reinforced the need for revamping the healthcare service delivery systems around the world to meet the increased challenges of modern-day illnesses. The use of medical cyber–physical system (MCPS) ... -
The impact of serialisation on operational efficiency and productivity in pharmaceutical sites: A literature review
(Taylor & Francis, 2023-07-04)Serialization technology was introduced to protect the pharmaceutical supply chain from falsified and substandard medicines infiltration. The implementation of serialization systems required a substantial investment by ... -
Implementation of a Lean 4.0 project to reduce non-value add waste in a medical device company
(MDPI, 2022-11-22)The fourth industrial revolution, also referred to as Industry 4.0, has resulted in many changes within the manufacturing industry. The purpose of the study is to demonstrate how an Industry 4.0 project was scoped and ... -
Implementing a customised Lean Six Sigma methodology at a compound animal feed manufacturer in Ireland
(Emerald, 2023-01-27)This study aims to propose a tailored Lean Six Sigma framework providing an accessible Lean Six Sigma methodology for compound feed manufacturers with the aim of mitigating rising costs and increasingly complex demands ... -
Improving the finite element model accuracy of tissue engineered scaffolds produced by selective laser sintering
(Springer Verlag, 2015-01-13)In bone tissue engineering, both geometrical and mechanical properties of a scaffold play a major part in the success of the treatment. The mechanical stresses and strains that act on cells on a scaffold in a physiological ...