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Biomodels of bone: a review
(Springer, 2005)
In this paper, a definition of a biomodel is presented, based on which different specific types of biomodels are identified, viz., virtual biomodels, computational biomodels, and physical biomodels. The paper then focuses ...
Mechanisms of osteocyte stimulation in osteoporosis
(Elsevier, 2016-05-10)
Experimental studies have shown that primary osteoporosis' caused by oestrogen deficiency results in localised alterations in bone tissue properties and mineral composition. Additionally, changes to the lacunar-canalicular ...
The tensile ductility of cellular solids: the role of imperfections
(Elsevier, 2016-10-11)
Metallic and polymeric foams typically possess a low tensile failure strain of a few percent despite the fact that the parent solid can have high ductility (10% or more). This is remarkable as foams are bending-dominated ...
Selective laser sintering of hydroxyapatite/poly-epsilon-caprolactone scaffolds
(2010)
Selective laser sintering (SLS) enables the fabrication of complex geometries with the intricate and controllable internal architecture required in the field of tissue engineering. In this study hydroxyapatite and ...
Effect of hydroxyapatite on biodegradable scaffolds fabricated by SLS
(Trans Tech Publications Ltd., 2009)
Selective laser sintering (SLS) has the potential to fabricate bioresorbable polymer / ceramic composite scaffolds with pre-designed external and internal architecture that can be used for bone tissue engineering applications. ...
Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation
(Elsevier, 2013-07-18)
Osteocytes are terminally differentiated bone cells, derived from
osteoblasts, which are vital for regulation of bone formation and resorption. ECM stiffness and cell seeding
density have been shown to regulate osteoblast ...
Single Cyclized Molecule Structure from RAFT Homopolymerization of Multi-vinyl Monomers
(2012)
We explore a kinetically controlled strategy to suppress the gelation in the homopolymerization of multi-vinyl monomers (MVMs) via RAFT polymerization. We report the generation of 3D single cyclized polymer structures from ...
Evaluating the effect of increasing ceramic content on the mechanical properties, material microstructure and degradation of selective laser sintered PCL/b-TCP materials
(Elsevier, 2015-06-06)
Orthopaedic scaffold materials were fabricated from polycaprolactone (PCL) and composite PCL β-tricalcium phosphate (PCL/β-TCP) powders using selective laser sintering (SLS). Incorporating β-TCP particles is ...
A three-scale finite element investigation into the effects of tissue mineralisation and lamellar organisation in human cortical and trabecular bone
(Elsevier, 2012-03-20)
Bone is an exceptional material that is lightweight for efficient movement but also exhibits excellent strength and stiffness imparted by a composite material of organic proteins and mineral crystals that are intricately ...
Experimental mechanical testing of Poly (l-Lactide) (PLLA) to facilitate pre-degradation characteristics for application in cardiovascular stenting
(Elsevier, 2016-07-19)
Next-generation stents made from Biodegradable Polymers (BPs) aim to address the long-term risks (i.e. late restenosis and in-stent thrombosis) associated with both Bare Metal Stents and Drug Eluting Stents, whilst aiming ...