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dc.contributor.authorKeating, Aileen F.
dc.contributor.authorSmith, Terry J.
dc.contributor.authorCairns, Michael T.
dc.date.accessioned2016-05-20T10:24:40Z
dc.date.available2016-05-20T10:24:40Z
dc.date.issued2008
dc.identifier.citationKeating, AF,Smith, TJ,Ross, RP,Cairns, MT (2008) 'A note on the evaluation of a beta-casein variant in bovine breeds by allele-specific PCR and relevance to beta-casomorphin'. Irish Journal Of Agricultural And Food Research, 47 :99-104.en_IE
dc.identifier.issn2009-9029
dc.identifier.urihttp://hdl.handle.net/10379/5821
dc.descriptionJournal articleen_IE
dc.description.abstractTwo genetic variants of the bovine beta-casein gene (A(1) and B) encode a histidine residue at codon 67, resulting in potential liberation of a bioactive peptide, beta-casomorphin, upon digestion. An allele-specific PCR (AS-PCR) was evaluated to distinguish between the beta-casomorphin-releasing variants (A(1) and B) and the non-releasing variants. AS-PCR successfully distinguished P-casein variants in 41 of 42 animals as confirmed by sequence analysis. Overall, while the incidence of the homozygous A, and B animals (i.e., homozygous for the histidine residue; 21.4%) was lower than that for animals without the histidine residue (30.9% respectively), 69% of animals carried at least one allele for the histidine residue at codon 67.en_IE
dc.description.sponsorshipTeagasc; Enterprise Irelanden_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherTeagasc; De Gruyter Openen_IE
dc.relation.ispartofIrish Journal Of Agricultural And Food Researchen
dc.subjectAllele-specific PCRen_IE
dc.subjectBeta-caseinen_IE
dc.subjectBioactive peptidesen_IE
dc.subjectAmplificationen_IE
dc.subjectProteinsen_IE
dc.subjectMilken_IE
dc.titleA note on the evaluation of a beta-casein variant in bovine breeds by allele-specific PCR and relevance to beta-casomorphinen_IE
dc.typeArticleen_IE
dc.date.updated2016-05-17T10:21:58Z
dc.local.publishedsourcehttp://www.jstor.org/stable/25564579en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|
dc.internal.rssid1334308
dc.local.contactMichael Cairns, Glycoscience Group, Ncbes, Biomedical Sciences, Dangan, Newcastle Rd. 2094 Email: michael.cairns@nuigalway.ie
dc.local.copyrightcheckedNo
dc.local.versionACCEPTED
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