Search
Now showing items 1-5 of 5
Maternal deprivation is associated with sex-dependent alterations in nociceptive behavior and neuroinflammatory mediators in the rat following peripheral nerve injury
(Elsevier, 2013-10)
Early-life stress is associated with an increased risk of developing affective disorders and chronic pain conditions. This study examined the effect of maternal deprivation (MD) on nociceptive responding prior to and ...
Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala
(Wiley, 2013-08-29)
The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ...
Anandamide modulation of endotoxin-induced inflammation
(OMICS International, 2013-12-20)
The endocannabinoid system is comprised of the CB1
and CB2
receptors, the naturally occurring endogenous ligands, anandamide
(AEA) and 2-arachidonyl glycerol (2-AG); and the enzymes
involved in their synthesis and ...
Relationship between epithelial and stromal TRIM28 expression predicts survival in colorectal cancer patients
(Wiley, 2013-02-21)
Background and Aim
TRIM28 is a multi‐domain nuclear protein with pleotropic effects in both normal and tumor cells. In this study, TRIM28 expression in epithelial and stromal tumor microenvironment and its prognostic role ...
A role for PPARα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats
(Wiley, 2013-12-05)
Background and Purpose
The nuclear hormone receptor, PPARα, and its endogenous ligands, are involved in pain modulation. PPARα is expressed in the medial prefrontal cortex (mPFC), a key brain region involved in both the ...