Browsing Physiology (Scholarly Articles) by Subject "PHARMACOLOGICAL INHIBITION"
Now showing items 1-3 of 3
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Endocannabinoid modulation of inflammatory hyperalgesia in the IFN-α mouse model of depression
(Elsevier, 2019-09-07)Depression is a well-recognised effect of long-term treatment with interferon-alpha (IFN-alpha), a widely used treatment for chronic viral hepatitis and malignancy. In addition to the emotional disturbances, high incidences ... -
FAAH inhibition attenuates TLR3-mediated hyperthermia, nociceptive- and anxiety-like behaviour in female rats
(Elsevier, 2018-06-25)Aberrant activation of toll-like receptor (TLR)s results in persistent and prolonged neuroinflammation and has been implicated in the pathogenesis and exacerbation of psychiatric and neurodegenerative disorders. TLR3 ... -
FAAH, but not MAGL, inhibition modulates acute TLR3‐induced neuroimmune signaling in the rat, independent of sex
(Wiley, 2017-07-20)Toll-like receptor (TLR)3 is a key component of the innate immune response to viral infection. The present study firstly examined whether sex differences exist in TLR3-induced inflammatory, endocrine, and sickness responses. ...