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dc.contributor.authorDestrade, Michel
dc.contributor.authorLiu, Yi
dc.contributor.authorMurphy, Jeremiah G.
dc.contributor.authorKassab, Ghassan S.
dc.date.accessioned2016-03-02T15:26:15Z
dc.date.available2016-03-02T15:26:15Z
dc.date.issued2012-06-21
dc.identifier.citationM. Destrade, Y. Liu , J.G. Murphy , G.S. Kassab (2012) 'Uniform transmural strain in pre-stressed arteries occurs at physiological pressure'. Journal Of Theoretical Biology, 303 :93-97.en_IE
dc.identifier.issn1095-8541
dc.identifier.urihttp://hdl.handle.net/10379/5595
dc.description.abstractResidual deformation (strain) exists in arterial vessels, and has been previously proposed to induce homogeneous transmural strain distribution. In this work, we present analytical formulations that predict the existence of a finite internal (homeostatic) pressure for which the transmural deformation is homogenous, and the corresponding stress field. We provide evidence on the physical existence of homeostatic pressure when the artery is modeled as an incompressible tube with orthotropic constitutive strain-energy function. Based on experimental data of rabbit carotid arteries and porcine coronary arteries, the model predicts a homeostatic mean pressure of ∼90 mmHg and 70 120 mmHg, respectively. The predictions are well within the physiological pressure range. Some consequences of this strain homogeneity in the physiological pressure range are explored under the proposed assumptions.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherElsevieren_IE
dc.relation.ispartofJournal Of Theoretical Biologyen
dc.subjectMathematical modelingen_IE
dc.subjectArterial tissueen_IE
dc.subjectHomeostatic strainen_IE
dc.subjectResidual strainen_IE
dc.subjectOpening angleen_IE
dc.titleUniform transmural strain in pre-stressed arteries occurs at physiological pressureen_IE
dc.typeArticleen_IE
dc.date.updated2015-10-09T08:26:39Z
dc.identifier.doi10.1016/j.jtbi.2012.03.010
dc.local.publishedsourcehttp://www.sciencedirect.com/science/article/pii/S0022519312001270en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|1267875|~|
dc.internal.rssid6257190
dc.local.contactMichel Destrade, Room Adb-1002, Áras De Brun, School Of Mathematics, Nui Galway. 2344 Email: michel.destrade@nuigalway.ie
dc.local.copyrightcheckedNo
dc.local.versionPUBLISHED
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