Browsing Biochemistry (Scholarly Articles) by Author "O'Dwyer, Michael"

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    • Neurotrophins and B-cell malignancies 

      Gorman, Adrienne; Hillis, Jennifer; O'Dwyer, Michael (Springer Verlag, 2015-09-23)
      Neurotrophins and their receptors act as important proliferative and pro-survival factors in a variety of cell types. Neurotrophins are produced by multiple cell types in both pro and mature forms, and can act in an autocrine ...

    • The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis 

      van Dijk, Marianne; Murphy, Eoin; Morrell, Ruth; O'Dwyer, Michael; Szegezdi, Eva; Samali, Afshin (2011)
      Acute myeloid leukemia (AML) is an aggressive stem cell malignancy that is difficult to treat. There are limitations to the current treatment regimes especially after disease relapse, and therefore new therapeutic agents ...