Browsing Biochemistry (Scholarly Articles) by Title
Now showing items 39-41 of 41
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Stress management at the ER: regulators of ER stress-induced apoptosis.
(Elsevier, 2012-02-17)The endoplasmic reticulum (ER) is an elaborate cellular organelle essential for cell function and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins which are ... -
SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation
(Wiley Open Access and Federation of European Biochemical Societies, 2022-01-24)The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase ¿-primase (Pol-prim). Since cellular ... -
SV40 T antigen interactions with ssDNA and replication protein A: a regulatory role of T antigen monomers in lagging strand DNA replication
(Oxford University Press (OUP), 2020-03-04)DNA replication is a central process in all living organisms. Polyomavirus DNA replication serves as a model system for eukaryotic DNA replication and has considerably contributed to our understanding of basic replication ...