Now showing items 1-2 of 2

    • RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells 

      Jaafar, Rola; Mnich, Katarzyna; Dolan, Sarah; Hillis, Jennifer; Almanza, Aitor; Logue, Susan E.; Samali, Afshin; Gorman, Adrienne M. (Elsevier, 2018-02-06)
      Receptor-interacting protein 2 (RIP2) is an essential mediator of inflammation and innate immunity, but little is known about its role outside the immune system. Recently, RIP2 has been linked to chemoresistance of triple ...
    • Stress management at the ER: regulators of ER stress-induced apoptosis. 

      Gorman, Adrienne M.; Healy, Sandra J.M.; Jäger, Richard; Samali, Afshin (Elsevier, 2012-02-17)
      The endoplasmic reticulum (ER) is an elaborate cellular organelle essential for cell function and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins which are ...