Browsing CÚRAM - Centre for Research in Medical Devices (Scholarly Articles) by Type "Article"
Now showing items 1-20 of 37
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Advancements and challenges in multidomain multicargo delivery vehicles
(Wiley, 2018-02-15)Reparative and regenerative processes are well‐orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available ... -
Analysis of a poly(ε-decalactone)/silver nanowire composite as an electrically conducting neural interface biomaterial
(BMC (part of Springer Nature), 2019-04-15)Advancement in polymer technologies, facilitated predominantly through chemical engineering approaches or through the identification and utilization of novel renewable resources, has been a steady focus of biomaterials ... -
Applicability of FTIR-ATR method to measure carbonyls in blood plasma after physical and mental stress
(Hindawi, 2019-03-26)Introduction. Oxidative stress is a state of imbalance between the production of reactive oxygen species and antioxidant defenses. It results in the oxidation of all cellular elements and, to a large extent, proteins, ... -
Automation, monitoring, and standardization of cell product manufacturing
(Frontiers Media, 2020-07-14)Although regenerative medicine products are at the forefront of scientific research, technological innovation, and clinical translation, their reproducibility and large-scale production are compromised by automation, ... -
Bioactive potential of natural biomaterials: identification, retention and assessment of biological properties
(Springer Nature, 2021-03-19)Biomaterials have had an increasingly important role in recent decades, in biomedical device design and the development of tissue engineering solutions for cell delivery, drug delivery, device integration, tissue replacement, ... -
Biophysics rules the cell culture but has yet to reach the clinic: Why is that?
(Lippincott, Williams & Wilkins, 2017-07)Musculoskeletal injuries are the leading cause of physical disability worldwide, with associated annual direct and indirect healthcare expenditure in excess of $874 billion in the United States alone.1 Current treatments ... -
Characterization of the ‘White’ appearing clots that cause acute ischemic stroke
(Elsevier, 2021-09-28)Objectives Most clots retrieved from patients with acute ischemic stroke are ‘red’ in color. ‘White’ clots represent a less common entity and their histological composition is less known. Our aim was to investigate the ... -
The chemistry and topography of stabilized and functionalized graphene oxide coatings
(Wiley, 2018-08-01)Graphene oxide (GO) thin films and coatings are regarded as superior in quality to other materials especially for biomedical applications. However, the lack of stability and understanding of their structure and defects ... -
Chirality-sorted carbon nanotube films as high capacity electrode materials
(Royal Society of Chemistry, 2018-08-30)Carbon nanomaterials show great promise for a wide range of applications due to their excellent physicochemical and electrical properties. Since their discovery, the state-of-the-art has expanded the scope of their application ... -
The collagen suprafamily: From biosynthesis to advanced biomaterial development
(Wiley, 2018-08-20)Collagen is the oldest and most abundant extracellular matrix protein that has found many applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview of the family of collagens and their ... -
Current and upcoming therapies to modulate skin scarring and fibrosis
(Elsevier, 2018-08-30)Skin is the largest organ of the human body. Being the interface between the body and the outer environment, makes it susceptible to physical injury. To maintain life, nature has endowed skin with a fast healing response ... -
Electric field stimulation for tissue engineering applications
(BMC (part of Springer Nature), 2021-01-05)Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation ... -
Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: Cytocompatibility and electrochemical studies
(Elsevier, 2019-02-06)Conducting polymers have been extensively reported as promising coating materials for applications involving interactions with electrically excitable tissues. Specifically, metal electrodes functionalized with conducting ... -
Evaluation of drug loading capacity and release characteristics of PEDOT/naproxen system: Effect of doping ions
(Elsevier, 2018-09-08)Conducting polymers are versatile and robust materials that have recently become attractive as controlled drug delivery systems. Possessing ion exchangeable properties, they can serve as carriers for numerous biologically ... -
Fibrin as a scaffold for delivery of GDNF overexpressing stem cells to the adult rat brain
(2017-04-05)Treatment of neurodegenerative disease is entering a new era where direct intracerebral delivery of therapeutic factors aims to restore normality to dysfunctional circuits. Cell-based therapeutic approaches, where virally ... -
Fractal form PEDOT/Au assemblies as thin-film neural interface materials
(IOP Publishing, 2018-06-04)Electrically conducting polymer formulations have emerged as promising approaches for the development of interfaces and scaffolds in neural engineering, facilitating the development of physicochemically modified constructs ... -
Gene expression profiling identifies interferon signalling molecules and IGFBP3 in human degenerative annulus fibrosus
(Nature Publishing Group:, 2015-10-22)Low back pain is a major cause of disability especially for people between 20 and 50 years of age. As a costly healthcare problem, it imposes a serious socio-economic burden. Current surgical therapies fail to replace the ... -
A glycotherapeutic approach to functionalize biomaterials-based systems
(Wiley, 2020-03-18)In addition to being one of the primary building block materials of living cells, glycans are also favorable candidates for therapeutic applications. In the mid-20th century, the progress of glycans in the drug discovery ... -
High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke
(BMJ Publishing Group, 2020-12-23)Background: Characterization of acute ischemic stroke (AIS) clots has typically focused on two dimensional histological analysis of the thrombus. The three dimensional (3D) architecture and distribution of components ... -
Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy
(BMJ Publishing Group, 2021-05-11)Background Several animal studies have demonstrated that mechanical thrombectomy (MT) for acute ischemic stroke (AIS) may cause vessel wall injury (VWI). However, the histological changes in human cerebral arteries following ...