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Recent advances in host–guest self‐assembled cyclodextrin carriers: Implications for responsive drug delivery and biomedical engineering
(Wiley, 2020-02-05)
This Review is an overview of the unique characteristics of cyclodextrin in forming an inclusion complex via host guest noncovalent interactions. The modification of cyclodextrin advances its application as a pharmaceutical ...
In vitro attenuation of astrocyte activation and neuroinflammation through ibuprofen-doping of poly(3,4-ethylenedioxypyrrole) formulations
(Elsevier, 2020-04-08)
Neuroinflammation is often associated with poor functional recovery and may contribute to or initiate the development of severe neurological disorders, such as epilepsy, Parkinson's disease or Alzheimer's disease. Ibuprofen ...
Microwave ablation antenna for functional adenomas in the adrenal gland
(IEEE, 2020-03-02)
Microwave thermal ablation has been thoroughly investigated in the last decades. However, new challenges for this technology are nowadays represented by specific applications. The present work investigates a promising ...
The synergistic effect of low oxygen tension and macromolecular crowding in the development of extracellular matrix-rich tendon equivalents
(IOP Publishing, 2020-02-26)
Cellular therapies play an important role in tendon tissue engineering, with tenocytes being the most prominent and potent cell population available. However, for the development of a rich extracellular matrix tenocyte-assembled ...
A glycotherapeutic approach to functionalize biomaterials-based systems
(Wiley, 2020-03-18)
In addition to being one of the primary building block materials of living cells, glycans are also favorable candidates for therapeutic applications. In the mid-20th century, the progress of glycans in the drug discovery ...
High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke
(BMJ Publishing Group, 2020-12-23)
Background:
Characterization of acute ischemic stroke (AIS) clots has typically focused on two dimensional histological analysis of the thrombus. The three dimensional (3D) architecture and distribution of components ...
Automation, monitoring, and standardization of cell product manufacturing
(Frontiers Media, 2020-07-14)
Although regenerative medicine products are at the forefront of scientific research, technological innovation, and clinical translation, their reproducibility and large-scale production are compromised by automation, ...