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dc.contributor.authorGrogan, James A.
dc.contributor.authorLeen, Sean B.
dc.contributor.authorMcHugh, Peter E.
dc.date.accessioned2015-12-15T14:37:30Z
dc.date.available2015-12-15T14:37:30Z
dc.date.issued2012-03-02
dc.identifier.citationGrogan, JA,Leen, SB,McHugh, PE (2012) 'Comparing coronary stent material performance on a common geometric platform through simulated bench testing'. Journal Of The Mechanical Behavior Of Biomedical Materials, 12 :129-138.en_IE
dc.identifier.issn1751-6161
dc.identifier.urihttp://hdl.handle.net/10379/5405
dc.descriptionJournal articleen_IE
dc.description.abstractAbsorbable metallic stents (AMSs) are a newly emerging cardiovascular technology which has the potential to eliminate long-term patient health risks associated with conventional permanent stents. AMSs developed to date have consisted of magnesium alloys or iron, materials with inferior mechanical properties to those used in permanent stents, such as stainless steel and cobalt-chromium alloys. However, for AMSs to be feasible for widespread clinical use it is important that their performance is comparable to modem permanent stents. To date, the performances of magnesium, iron, and permanent stent materials have not been compared on a common stent platform for a range of stent performance metrics, such as flexibility, radial strength, and recoil. In this study, this comparison is made through simulated bench testing, based on finite-element modelling. The significance of this study is that it allows potential limitations in current AMS performance to be identified, which will aid in focusing future AMS design. This study also allows the identification of limitations in current AMS materials, thereby informing the on-going development of candidate biodegradable alloys. The results indicate that the AMSs studied here can match the recoil characteristics and radial strength of modern permanent stents; however, to achieve this, larger strut dimensions are required. It is also predicted that the AMSs studied are inferior to permanent stents in terms of maximum absolute curvature and longitudinal stiffness. (C) 2012 Elsevier Ltd. All rights reserved.en_IE
dc.description.sponsorshipSFI / HEA Irish Centre for High End Computing (ICHEC)en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherElsevier ScienceDirecten_IE
dc.relation.ispartofJournal Of The Mechanical Behavior Of Biomedical Materialsen
dc.subjectFinite-element analysisen_IE
dc.subjectBiodegradable ironen_IE
dc.subjectBiodegradable magnesiumen_IE
dc.subjectAbsorbable metallic stentsen_IE
dc.subjectFinite element methoden_IE
dc.subjectImplantationen_IE
dc.subjectFlexibilityen_IE
dc.subjectBehavioren_IE
dc.subjectDesignen_IE
dc.subjectStrutsen_IE
dc.titleComparing coronary stent material performance on a common geometric platform through simulated bench testingen_IE
dc.typeArticleen_IE
dc.date.updated2015-12-07T13:08:04Z
dc.identifier.doi10.1016/j.jmbbm.2012.02.013
dc.local.publishedsourcehttp://dx.doi.org/10.1016/j.jmbbm.2012.02.013en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|
dc.internal.rssid2553392
dc.local.contactSean Leen, Mechanical & Biomedical Eng, Eng-2051, New Engineering Building, Nui Galway. 5955 Email: sean.leen@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionPUBLISHED
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