Show simple item record

dc.contributor.advisor
dc.contributor.authorLohfeld, Stefan
dc.date.accessioned2015-12-01T19:50:29Z
dc.date.available2015-12-01T19:50:29Z
dc.date.issued2009
dc.identifier.citationEosoly, S.; Lohfeld, S.; Brabazon, D. (2009) 'Effect of hydroxyapatite on biodegradable scaffolds fabricated by SLS'. Key Engineering Materials, 396-398 :659-662.en_IE
dc.identifier.urihttp://hdl.handle.net/10379/5357
dc.descriptionJournal articleen_IE
dc.description.abstractSelective laser sintering (SLS) has the potential to fabricate bioresorbable polymer / ceramic composite scaffolds with pre-designed external and internal architecture that can be used for bone tissue engineering applications. Scaffolds were fabricated using poly-ε-caprolactone as the base material. The effect of 15 and 30 wt% of hydroxyapatite (HA) addition was investigated in terms of compressive properties, accuracy, surface topology, and wettability. Fabricated dimensions of PCL microstructures showed great deviations from their nominal values. Average surface roughness was found to be Ra=25±4 μm. Increased HA content had no statistically significant effect on accuracy and surface roughness. However the addition of HA had a significant influence on compressive properties, hydrophobicity and wettability of the samples. Addition of 30 wt% HA improved initial compressive modulus of pure PCL scaffolds from 1.31±0.08 MPa to 1.58±0.18 MPa. Yield strength values increased from 0.14±0.07 MPa to 0.17±0.01 MPa by adding 15 wt% of HA, but decreased with further HA addition. Yield strain for all compositions was over ε=0.06. Increased HA content decreased hydrophobicity and increased wettability of scaffold surfaces. The study demonstrated the ability of SLS to fabricate tissue engineering scaffolds, and the positive effect of HA particle reinforcement in terms of compressive mechanical properties and surface characteristics.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherTrans Tech Publications Ltd.en_IE
dc.relation.ispartofKey Engineering Materialsen
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectSelective laser sinteringen_IE
dc.subjectBone scaffolden_IE
dc.subjectHydroxyapatiteen_IE
dc.titleEffect of hydroxyapatite on biodegradable scaffolds fabricated by SLSen_IE
dc.typeArticleen_IE
dc.date.updated2015-11-25T16:01:32Z
dc.identifier.doi10.4028/www.scientific.net/KEM.396-398.659
dc.local.publishedsourcehttp://dx.doi.org/10.4028/www.scientific.net/KEM.396-398.659en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|
dc.internal.rssid1328840
dc.local.contactStefan Lohfeld, Mechanical & Biomedical Eng, Engineering Building Eng-1042, Nui Galway. 2963 Email: stefan.lohfeld@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionACCEPTED
nui.item.downloads160


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland