Show simple item record

dc.contributor.authorDestrade, Michel
dc.contributor.authorGilchrist, Michael D.
dc.date.accessioned2014-11-17T12:39:25Z
dc.date.available2014-11-17T12:39:25Z
dc.date.issued2012
dc.identifier.citationB. Rashid, M. Destrade, M.D. Gilchrist (2012) Hyperelastic and viscoelastic properties of brain tissue in tension ASME 2012 International Mechanical Engineering Congress & Exposition Houston, USA, 2012-11-09- 2014-11-15en_US
dc.identifier.isbn978-0-7918-4518-9
dc.identifier.urihttp://hdl.handle.net/10379/4737
dc.descriptionConference paperen_US
dc.description.abstractMechanical characterization of brain tissue at high loading velocities is particularly important for modelling Traumatic Brain Injury (TBI). During severe impact conditions, brain tissue experiences a mixture of compression, tension and shear. Diffuse axonal injury (DAI) occurs in animals and humans when the strains and strain rates exceed 10% and 10/s, respectively. Knowing the mechanical properties of brain tissue at these strains and strain rates is thus of particular importance, as they can be used in finite element simulations to predict the occurrence of brain injuries under different impact conditions.  In this research, uniaxial tensile tests at strain rates of 30, 60 and 90/s up to 30% strain and stress relaxation tests in tension at various strain magnitudes (10% - 60%) with an average rise time of 24 ms were performed. The brain tissue showed a stiffer response with increasing strain rates, showing that hyperelastic models are not adequate and that viscoelastic models are required. Specifically, the tensile engineering stress at 30% strain was 3.1 ± 0.49 kPa, 4.3 ± 0.86 kPa, 6.5 ± 0.76 kPa (mean ± SD) at strain rates of 30, 60 and 90/s, respectively. The Prony parameters were estimated from the relaxation data. Numerical simulations were performed using a one-term Ogden model to analyze hyperelastic and viscoelastic behavior of brain tissue up to 30% strain. The material parameters obtained in this study will help to develop biofidelic human brain finite element models, which subsequently can be used to predict brain injuries under impact conditions. en_US
dc.description.sponsorshipIRCSETen_US
dc.formatapplication/pdfen_US
dc.language.isoenen_US
dc.publisherASMEen_US
dc.relation.ispartofASME 2012 International Mechanical Engineering Congress & Expositionen
dc.subjectBiological tissuesen_US
dc.subjectBrainen_US
dc.subjectTensionen_US
dc.titleHyperelastic and viscoelastic properties of brain tissue in tensionen_US
dc.typeConference Paperen_US
dc.date.updated2014-11-15T12:47:27Z
dc.local.publishedsourcehttp://proceedings.asmedigitalcollection.asme.org/proceeding.aspx?articleid=1750485en_US
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|IRCSET|~|
dc.internal.rssid7644111
dc.local.contactMichel Destrade, Room C202 Áras De Brún, School Of Mathematics, Nui Galway. Email: michel.destrade@nuigalway.ie
dc.local.copyrightcheckedNo
dc.local.versionPUBLISHED
nui.item.downloads538


Files in this item

Attribution-NonCommercial-NoDerivs 3.0 Ireland
This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. Please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.

The following license files are associated with this item:

Thumbnail

This item appears in the following Collection(s)

Show simple item record