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The secretome derived from mesenchymal stromal cells cultured in a xeno-free medium promotes human cartilage recovery in vitro

Palama, Maria Elisabetta Federica; Shaw, Georgina Margaret; Carluccio, Simonetta; Reverberi, Daniele; Sercia, Laura; Persano, Luana; Pisignano, Dario; Cortese, Katia; Barry, Francis Peter; Murphy, Josephine Mary; Gentili, Chiara (Frontiers Media, 2020-02-14)

Osteoarthritis (OA) is a disabling joint disorder causing articular cartilage degeneration. Currently, the treatments are mainly aimed to pain and symptoms relief, rather than disease amelioration. Human bone marrow stromal ...