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dc.contributor.authorHeraty, Kevin B.
dc.contributor.authorLaffey, John G.
dc.contributor.authorQuinlan, Nathan J.
dc.date.accessioned2013-05-20T11:50:32Z
dc.date.available2013-05-20T11:50:32Z
dc.date.issued2008-11
dc.identifier.citationHeraty, KB,Laffey, JG,Quinlan, NJ (2008) 'Fluid dynamics of gas exchange in high-frequency oscillatory ventilation: In vitro investigations in idealized and anatomically realistic airway bifurcation models'. Annals Of Biomedical Engineering, 36 :1856-1869.en_US
dc.identifier.urihttp://hdl.handle.net/10379/3447
dc.description.abstractThe objective of this work is to develop understanding of the local fluid dynamic mechanisms that underpin gas exchange in high-frequency oscillatory ventilation (HFOV). The flow field during HFOV was investigated experimentally using particle image velocimetry in idealized and realistic models of a single bifurcation. Results show that inspiratory and expiratory fluid streams coexist in the airway at flow reversal, and mixing between them is enhanced by secondary flow and by vortices associated with shear layers. Unsteady flow separation and recirculation occurs in both geometries. The magnitude of secondary flow is greater in the realistic model than in the idealized model, and the structure of secondary flow is quite different. However, other flow structures are qualitatively similar.en_US
dc.description.sponsorshipIRCSET, Nationial Development Plan, Millenium Research Funden_US
dc.formatapplication/pdfen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAnnals Of Biomedical Engineeringen
dc.subjectRespiratory flowen_US
dc.subjectMechanical ventilationen_US
dc.subjectLungen_US
dc.subjectParticle image velocimetryen_US
dc.titleFluid dynamics of gas exchange in high-frequency oscillatory ventilation: In vitro investigations in idealized and anatomically realistic airway bifurcation modelsen_US
dc.typeArticleen_US
dc.date.updated2013-05-16T15:26:55Z
dc.identifier.doiDOI 10.1007/s10439-008-9557-1
dc.local.publishedsourcedx.doi.org/10.1007/s10439-008-9557-1en_US
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|
dc.internal.rssid1334681
dc.local.contactNathan Quinlan, Mechanical & Biomedical Eng, Eng-2042, New Engineering Building, Nui Galway. 2726 Email: nathan.quinlan@nuigalway.ie
dc.local.copyrightcheckedNo
dc.local.versionACCEPTED
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