Browsing The Ryan Institute (Scholarly Articles) by Author "Donnelly, Sheila"
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Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
Cwiklinski, Krystyna; Robinson, Mark W.; Donnelly, Sheila; Dalton, John P. (BMC, 2021-01-11)Background The major pathogenesis associated with Fasciola hepatica infection results from the extensive tissue damage caused by the tunnelling and feeding activity of immature flukes during their migration, growth and ... -
Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)
Shiels, Jenna; Cwiklinski, Krystyna; Alvarado, Raquel; Thivierge, Karine; Cotton, Sophie; Gonzales Santana, Bibiana; To, Joyce; Donnelly, Sheila; Taggart, Clifford C.; Weldon, Sinead; Dalton, John P. (Public Library of Science, 2020-07-09)Sm16, also known as SPO-1 and SmSLP, is a low molecular weight protein (~16kDa) secreted by the digenean trematode parasite Schistosoma mansoni, one of the main causative agents of human schistosomiasis. The molecule is ... -
Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)
Shiels, Jenna; Cwiklinski, Krystyna; Alvarado, Raquel; Thivierge, Karine; Cotton, Sophie; Gonzales Santana, Bibiana; To, Joyce; Donnelly, Sheila; Taggart, Clifford C.; Weldon, Sinead; Dalton, John P. (Public Library of Science, 2020-07-09)Background Sm16, also known as SPO-1 and SmSLP, is a low molecular weight protein (~16kDa) secreted by the digenean trematode parasite Schistosoma mansoni, one of the main causative agents of human schistosomiasis. The ...