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Now showing items 1-10 of 17
Considering time in migration and border control practices
(Inderscience, 2016-10)
Practices within the area of migration and border control are often
analysed through a spatial lens. This is understandable: migration studies deal
with movement of people across different places and spaces. Internatio ...
Semantic representation and enrichment of information retrieval experimental data
(Springer Berlin Heidelberg, 2016-05-28)
Experimental evaluation carried out in international large-scale campaigns is a fundamental pillar of the scientific and technological advancement of information retrieval (IR) systems. Such evaluation activities produce ...
Sterile post-traumatic immunosuppression
(Nature Publishing Group, 2016-04-29)
After major trauma, the human immune system initiates a series of inflammatory events at the injury site that is later followed by suppression of local inflammation favoring the repair and remodeling of the damaged tissues. ...
Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice
(Wiley, 2016-12-28)
Up to now long-term in vitro growth of pro-B cells was thought to require stromal cells. However, here we show that fetal liver (FL) and bone marrow (BM) derived pro-B cells can be propagated long-term in stromal cell-free ...
Development of a flow cytometry-based potency assay for measuring the in vitro immunomodulatory properties of mesenchymal stromal cells
(Elsevier, 2016-07-20)
Human bone marrow-derived mesenchymal stromal/stem cells (MSC) have well-documented modulatory effects on multiple immune cell types. Although these effects are linked to their therapeutic benefit in diverse diseases, a ...
Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint
(Company of Biologists, 2016)
During mitotic arrest induced by microtubule targeting drugs, the weakening of the spindle assembly checkpoint (SAC) allows cells to progress through the cell cycle without chromosome segregation occurring. PLK1 kinase ...
Effects of combined progesterone and 17 beta-estradiol treatment on the transcriptome of cultured human myometrial smooth muscle cells
(American Physiological Society, 2016-01-01)
A transcriptomic analysis of cultured human uterine smooth muscle cells (hUtSMCs) was performed to examine gene expression profiles in smooth muscle in an environment containing the two major steroid hormones that regulate ...
Differentiation of vascular stem cells contributes to ectopic calcification of atherosclerotic plaque
(Wiley, 2016-02-27)
The cellular and molecular basis of vascular calcification (VC) in atherosclerosis is not fully understood. Here, we investigate role of resident/circulating progenitor cells in VC and contribution of inflammatory plaque ...
Implications of the UK HGV road user charge for Irish export freight transport stakeholders. A qualitative study
(Elsevier, 2016-04-13)
Road user charging in the European Union has evolved from a mechanism of financing the construction and maintenance of motorways to internalising the road user costs in line with the polluter pays principle. The United ...
Magnetotelluric tensors, electromagnetic field scattering and distortion in three-dimensional environments
(American Geophysical Union, 2016-10-28)
This paper describes how subsurface resistivity distributions can be estimated directly from
the magnetotelluric (MT) tensor relationship between electric and magnetic fields observed on a
three-dimensional (3-D) half-space. ...