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Spinal cord injury in vitro: Modelling axon growth inhibition
(Elsevier, 2010-06)
Over the past three decades, tremendous progress has been made in elucidating mechanisms underlying regenerative failure after spinal cord injury and in devising therapeutic approaches to promote functional nerve regeneration. ...
Wound healing and scar wars
(Elsevier, 2018-06-15)
Wound healing and scarring are highly conserved physiological responses to wounding in most tissues in higher organisms, consisting of a sequence of well-characterised stages (coagulation, inflammation, proliferation and ...
Nano-textured self-assembled aligned collagen hydrogels promote directional neurite guidance and overcome inhibition by myelin associated glycoprotein
(Royal Society of Chemistry, 2011-01-11)
The development of nerve guidance conduits is constantly evolving as the need arises for therapies for spinal cord injury. In addition to providing a path for regrowing axons to reconnect with their appropriate targets, ...
Advancements and challenges in multidomain multicargo delivery vehicles
(Wiley, 2018-02-15)
Reparative and regenerative processes are well‐orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available ...
Joint academic and industrial efforts towards innovative and efficient solutions for clinical needs
(Springer Verlag, 2018-07-31)
The 4th Translational Research Symposium (TRS) was organised at the annual meeting of the European Society for Biomaterials (ESB) 2017, Athens, Greece, with a focus on ‘Academia—Industry Clusters of Research for Innovation ...
Biophysics rules the cell culture but has yet to reach the clinic: Why is that?
(Lippincott, Williams & Wilkins, 2017-07)
Musculoskeletal injuries are the leading cause of physical disability worldwide, with associated annual direct and indirect healthcare expenditure in excess of $874 billion in the United States alone.1 Current treatments ...
Local pharmacological induction of angiogenesis: drugs for cells and cells as drugs
(Elsevier, 2019-06-19)
The past decades have seen significant advances in pro-angiogenic strategies based on delivery of molecules and cells for conditions such as coronary artery disease, critical limb ischemia and stroke. Currently, three major ...
The collagen suprafamily: From biosynthesis to advanced biomaterial development
(Wiley, 2018-08-20)
Collagen is the oldest and most abundant extracellular matrix protein that has found many applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview of the family of collagens and their ...
Hypoxia preconditioning of bone marrow mesenchymal stem cells before implantation in orthopaedics
(Lippincott, Williams & Wilkins, 2019-12-01)
[No abstract available]
Translational Research Symposium—collaborative efforts as driving forces of healthcare innovation
(Springer Verlag, 2019-12-02)
The 5th Translational Research Symposium was organised at the annual meeting of the European Society for Biomaterials 2018, Maastricht, the Netherlands, with emphasis on the future of emerging and smart technologies for ...