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Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction

Friel, Anne M,; Sexton, Donal J.; O'Reilly, Michael W.; Smith, Terry; Morrison, John J. (Society for Reproduction and Fertility, 2006-07-01)

Pre eclampsia represents a state of increased or prolonged vasoconstriction, partially linked to the potent vasocontractile effect of isoprostanes. The process of Rho A-mediated calcium sensitisation is inherent to a state ...