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dc.contributor.authorBonello, Julian
dc.contributor.authorElahi, Muhammad Adnan
dc.contributor.authorPorter, Emily
dc.contributor.authorO'Halloran, Martin
dc.contributor.authorFarrugia, Lourdes
dc.contributor.authorSammut, Charles V.
dc.identifier.citationBonello, Julian, Elahi, Muhammad Adnan, Porter, Emily, O’Halloran, Martin, Farrugia, Lourdes, & Sammut, Charles V. (2019). An investigation of the variation of dielectric properties of ovine lung tissue with temperature. Biomedical Physics & Engineering Express, 5(4), 045024. doi:10.1088/2057-1976/aaee40en_IE
dc.description.abstractPresently, lung cancer is the leading cause of cancer deaths. Microwave thermal ablation is commonly used for the treatment of lung cancer. During microwave ablation treatment, changing temperatures (up to 100 °C) cause variations in the dielectric properties of the tissue under treatment. This study investigates the temperature dependence of dielectric properties of ex-vivo ovine lung tissue. The frequency spectrum investigated was from 0.5 GHz to 8 GHz over a total of 201 points. In this study, a microwave ablator (MWA) and a microwave oven (MWO) were used to warm up the samples under investigation. Initially, the spectral variation of the dielectric properties with temperature are presented. The results show that both the real part of the permittivity and the conductivity decrease with temperature for both heating methodologies. The study also investigates the effect of the heating methodology on the measurements. In this case, MWA heating results in a wider range in the measured dielectric parameters compared to MWO. However, the average values for both methodologies are within experimental uncertainty. Finally, the study also presents the temperature coefficients for both the MWA and the MWO tissue heating methods. These results are useful in treatment planning of thermal ablation procedures in order to minimise thermal damage to peripheral tissue.en_IE
dc.description.sponsorshipThis work has received funding from the European Research Council under the European Union's Horizon 2020 Programme/ERC Grant Agreement BioElecPro n. 637780, and has been developed within the framework of COST Action MiMed (TD1301).en_IE
dc.publisherIOP Publishingen_IE
dc.relation.ispartofBiomedical Physics \& Engineering Expressen
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.subjectMicrowave ablationen_IE
dc.subjectdielectric propertiesen_IE
dc.subjecttemperature coefficientsen_IE
dc.titleAn investigation of the variation of dielectric properties of ovine lung tissue with temperatureen_IE
dc.contributor.funderEuropean Research Councilen_IE
dc.contributor.funderHorizon 2020en_IE
dc.local.contactMartin O'Halloran, School Of E&I/School Of Medicine, Nui Galway. 5072 Email:
dcterms.projectinfo:eu-repo/grantAgreement/EC/H2020::ERC::ERC-STG/637780/EU/Frontier Research on the Dielectric Properties of Biological Tissue/BIOELECPROen_IE

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Attribution-NonCommercial-NoDerivs 3.0 Ireland
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