Show simple item record

dc.contributor.authorLeader, Geraldine
dc.contributor.authorMurray, Maeve
dc.contributor.authorO’Súilleabháin, Páraic S.
dc.contributor.authorMaher, Leanne
dc.contributor.authorNaughton, Katie
dc.contributor.authorArndt, Sophia
dc.contributor.authorWhite, Keeley
dc.contributor.authorTraina, Ivan
dc.contributor.authorMannion, Arlene
dc.date.accessioned2020-10-13T09:18:46Z
dc.date.issued2020-05-28
dc.identifier.citationLeader, Geraldine, Murray, Maeve, O’Súilleabháin, Páraic S., Maher, Leanne, Naughton, Katie, Arndt, Sophia, White, Keeley, Traina, Ivan, Mannion, Arlene. (2020). Relationship between parent-reported gastrointestinal symptoms, sleep problems, autism spectrum disorder symptoms, and behavior problems in children and adolescents with 22q11.2 deletion syndrome. Research in Developmental Disabilities, 104, doi:10.1016/j.ridd.2020.103698en_IE
dc.identifier.issn0891-4222
dc.identifier.urihttp://hdl.handle.net/10379/16220
dc.description.abstractBackground: 22q11.2 deletion syndrome (22q) is a chromosome disorder, where a segment of chromosome 22, located at 811.2, is missing. This study aims to investigate the relationship between a number of parent-reported comorbid conditions including gastrointestinal symptoms, sleep problems, autism spectrum disorder (ASD) symptoms and behavior problems in children and adolescents with 22q deletion syndrome.Method: The Gastrointestinal Symptom Inventory, Children's Sleep Habits Questionnaire, Behavior Problem Inventory-Short Form and the Social Communication Questionnaire were completed by parents of 149 children and adolescents aged 3-18 years with a diagnosis of 22q.Results: A series of correlations and hierarchical multiple regressions were conducted to examine the relationships between GI symptoms, sleep problems and behavior problems in children and adolescents with 22q deletion syndrome. A significant moderate relationship was found between GI symptoms and sleep problems. Gender and ASD symptoms predicted GI symptoms. Significant small relationships were found between GI symptoms and self-injurious behavior. Significant small to moderate relationships were found between sleep problems and self-injurious behavior, aggressive/destructive behavior, and sterotyped behavior. Sleep problems predicted challenging behavior.Conclusions: This research demonstrated the importance of studying the relationship between comorbidities, including gastrointestinal symptoms, sleep problems, and behavior problems and how they shape the phenotype of 22q deletion syndrome.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherElsevieren_IE
dc.relation.ispartofResearch In Developmental Disabilitiesen
dc.subjectSOCIAL COMMUNICATION QUESTIONNAIREen_IE
dc.subjectATTENTION-DEFICIT/HYPERACTIVITY DISORDERen_IE
dc.subjectINVENTORY-SHORT FORMen_IE
dc.subjectCOMORBID PSYCHOPATHOLOGYen_IE
dc.subjectCHALLENGING BEHAVIORen_IE
dc.subjectPRESCHOOL-CHILDRENen_IE
dc.subjectINDIVIDUALSen_IE
dc.subjectDISABILITIESen_IE
dc.subjectEPILEPSYen_IE
dc.subjectFEATURESen_IE
dc.titleRelationship between parent-reported gastrointestinal symptoms, sleep problems, autism spectrum disorder symptoms, and behavior problems in children and adolescents with 22q11.2 deletion syndromeen_IE
dc.typeArticleen_IE
dc.date.updated2020-10-12T14:49:26Z
dc.identifier.doi10.1016/j.ridd.2020.103698
dc.local.publishedsourcehttps://doi.org/10.1016/j.ridd.2020.103698en_IE
dc.description.peer-reviewedpeer-reviewed
dc.description.embargo2021-05-28
dc.internal.rssid22340074
dc.local.contactArlene Mannion, Irish Centre For Autism, & Neurodevelopment Research, School Of Psychology, Nui Galway. Email: arlene.mannion@nuigalway.ie
dc.local.copyrightcheckedNo
dc.local.versionACCEPTED
nui.item.downloads0


Files in this item

Attribution-NonCommercial-NoDerivs 3.0 Ireland
This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. Please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.

The following license files are associated with this item:

Thumbnail

This item appears in the following Collection(s)

Show simple item record