Now showing items 1-4 of 4
Computational modelling of ovine critical-sized tibial defects with implanted scaffolds and prediction of the safety of fixator removal
Computational model geometries of tibial defects with two types of implanted tissue engineering scaffolds, β-tricalcium phosphate (β-TCP) and poly-ε-caprolactone (PCL)/β-TCP, are constructed from µ-CT scan images of the ...
Evaluating the effect of increasing ceramic content on the mechanical properties, material microstructure and degradation of selective laser sintered PCL/b-TCP materials
Orthopaedic scaffold materials were fabricated from polycaprolactone (PCL) and composite PCL β-tricalcium phosphate (PCL/β-TCP) powders using selective laser sintering (SLS). Incorporating β-TCP particles is ...
Modelling the degradation and elastic properties of poly(lactic-co-glycolic acid) films and regular open -cell tissue engineering scaffolds
Scaffolding plays a critical rule in tissue engineering and an appropriate degradation rate and sufficient mechanical integrity are required during degradation and healing of tissue. This paper presents a computational ...
The effect of substrate stiffness, thickness, and cross-linking density on osteogenic cell behavior
(Biophysical Society, 2015-04-07)
Osteogenic cells respond to mechanical changes in their environment by altering their spread area, morphology, and gene expression profile. In particular, the bulk modulus of the substrate, as well as its microstructure ...