Now showing items 1-3 of 3
Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes
(The Royal Society Publishing, 2012-06-06)
The osteocyte is believed to act as the main sensor of mechanical stimulus in bone, controlling signalling for bone growth and resorption in response to changes in the mechanical demands placed on our bones throughout life. ...
Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche
(AO Research Institute Davos, 2012)
Mesenchymal stem cells (MSCs) within their native environment of the stem cell niche in bone receive biochemical stimuli from surrounding cells. These stimuli likely influence how MSCs differentiate to become bone precursors. ...
A three-scale finite element investigation into the effects of tissue mineralisation and lamellar organisation in human cortical and trabecular bone
Bone is an exceptional material that is lightweight for efficient movement but also exhibits excellent strength and stiffness imparted by a composite material of organic proteins and mineral crystals that are intricately ...