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Evaluating the effect of increasing ceramic content on the mechanical properties, material microstructure and degradation of selective laser sintered PCL/b-TCP materials
(Elsevier, 2015-06-06)
Orthopaedic scaffold materials were fabricated from polycaprolactone (PCL) and composite PCL β-tricalcium phosphate (PCL/β-TCP) powders using selective laser sintering (SLS). Incorporating β-TCP particles is ...
3D Printing of Microspheres for Tissue Engineering Scaffolds
(Mary Ann Liebert, 2015-09)
Microspheres have tremendous potential as a scaffold material for tissue engineering applications due to their capability of encapsulation and controlled release of factors that assist tissue regeneration in the desired ...
Experimental mechanical testing of Poly (l-Lactide) (PLLA) to facilitate pre-degradation characteristics for application in cardiovascular stenting
(Elsevier, 2016-07-19)
Next-generation stents made from Biodegradable Polymers (BPs) aim to address the long-term risks (i.e. late restenosis and in-stent thrombosis) associated with both Bare Metal Stents and Drug Eluting Stents, whilst aiming ...
Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche
(AO Research Institute Davos, 2012)
Mesenchymal stem cells (MSCs) within their native environment of the stem cell niche in bone receive biochemical stimuli from surrounding cells. These stimuli likely influence how MSCs differentiate to become bone precursors. ...
Evaluation of a multiscale modelling methodology to predict the mechanical properties of PCL/β-TCP sintered scaffold materials
(Springer Verlag, 2014-12-02)
A multiscale modelling methodology to predict the macroscale stiffness of selective laser sintered polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) materials is evaluated. The relationship between a micromechanics-evaluated ...
Improving the finite element model accuracy of tissue engineered scaffolds produced by selective laser sintering
(Springer Verlag, 2015-01-13)
In bone tissue engineering, both geometrical and mechanical properties of a scaffold play a major part in the success of the treatment. The mechanical stresses and strains that act on cells on a scaffold in a physiological ...