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Altered mechanical environment of bone cells in an animal model of short- and long-term osteoporosis
(Biophysical Society, 2015-04-07)
Alterations in bone tissue composition during osteoporosis likely disrupt the mechanical environment of bone cells and may thereby initiate a mechanobiological response. It has proved challenging to characterize the ...
Thermally induced osteocyte damage initiates a remodelling signaling cascade
(Public Library of Science, 2015-03-18)
Thermal elevations experienced by bone during orthopaedic procedures, such as cutting and drilling, exothermal reactions from bone cement, and thermal therapies such as tumor ablation, can result in thermal damage leading ...
The effect of intraluminal contact mediated guidance signals on axonal mismatch during peripheral nerve repair
(Elsevier, 2012-06-25)
The current microsurgical gold standard for repairing long gap nerve injuries is the autograft. Autograft provides a protective environment for repair and a natural internal architecture, which is essential for regeneration. ...