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A Biomaterial Approach to Peripheral Nerve Regeneration: Bridging the Peripheral Nerve Gap and Enhancing Functional Recovery
(The Royal Society, 2011-11)
Microsurgical techniques for the treatment of large peripheral nerve injuries (such as the gold standard autograft) and its main clinically approved alternative 'hollow nerve guidance conduits (NGCs)' have a number of ...
Preferential cell response to anisotropic electro-spun fibrous scaffolds under tension-free conditions
Anisotropic alignment of collagen fibres in musculoskeletal tissues is responsible for the resistance to mechanical loading, whilst in cornea is responsible for transparency. Herein, we evaluated the response of tenocytes, ...
The effect of intraluminal contact mediated guidance signals on axonal mismatch during peripheral nerve repair
The current microsurgical gold standard for repairing long gap nerve injuries is the autograft. Autograft provides a protective environment for repair and a natural internal architecture, which is essential for regeneration. ...
Electromechanical properties of dried tendon and isoelectrically focused collagen hydrogels
Assembling artificial collagenous tissues with structural, functional, and mechanical properties which mimic natural tissues is of vital importance for many tissue engineering applications. While the electro-mechanical ...
Macromolecular crowding meets tissue engineering by self-ssembly: A paradigm shift in regenerative medicine
Advancements in molecular and cell biology have led to the development of cell-based therapies to treat injured or degenerated tissues.  The rationale of this concept is that functional regeneration can be achieved ...