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Alterations in the central opioid system following acute swim stress and olfactory bulbectomy in the rat

dc.contributor.authorMcHugh, K.
dc.contributor.authorP.Calcagno, P.
dc.contributor.authorCalcagno, P.
dc.contributor.authorFerdousi, M.
dc.contributor.authorSanchez, C.
dc.contributor.authorRoche, Michelle
dc.contributor.authorFinn, David P.
dc.contributor.authorKelly, John P.
dc.date.accessioned2020-01-22T12:14:31Z
dc.date.available2020-01-22T12:14:31Z
dc.date.issued2019-12-13
dc.identifier.citationMcHugh, K., Calcagno, P., Ferdousi, M., Sanchez, C., Roche, M., Finn, D. P., & Kelly, J. P. (2019). P.127 Alterations in the central opioid system following acute swim stress and olfactory bulbectomy in the rat. European Neuropsychopharmacology, 29, S105. doi: https://doi.org/10.1016/j.euroneuro.2019.09.181en_IE
dc.identifier.issn1873-7862
dc.identifier.urihttp://hdl.handle.net/10379/15722
dc.description.abstractIntroduction: Stress is a major component of many animal models of depression, induced acutely as in the forced swim test, or more long-term in the olfactory bulbectomy (OB) and chronic mild stress models [1]. The central opioid system has been implicated in regulating the stress response in rodents [2]. The objective of this study was to examine the effects of acute swim stress, and OB, alone or in combination, on opioid receptors and the precursors for their endogenous ligands in a number of brain regions implicated in stress/depression.en_IE
dc.description.sponsorshipThis abstract is financially supported by an educational grant from the Strategic Partnership Programme Grant from Science Foundation Ireland and Alkermes, Inc. (14/SPP/B3051).en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherElsevieren_IE
dc.relation.ispartofEuropean College of Neuropsychopharmacology (ECNP), 32nd ECNP Congressen
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectcentral opioid systemen_IE
dc.subjectacute swim stressen_IE
dc.subjectolfactory bulbectomyen_IE
dc.titleAlterations in the central opioid system following acute swim stress and olfactory bulbectomy in the raten_IE
dc.typeConference Paperen_IE
dc.date.updated2020-01-22T11:26:35Z
dc.identifier.doi10.1016/j.euroneuro.2019.09.181
dc.local.publishedsourcehttps://doi.org/10.1016/j.euroneuro.2019.09.181en_IE
dc.description.peer-reviewednon-peer-reviewed
dc.contributor.funderScience Foundation Irelanden_IE
dc.description.embargo2020-12-13
dc.internal.rssid19504421
dc.local.contactJohn Kelly, Dept. Of Pharmacology, & Therapeutics, Experimental Medicine Building, Nui Galway. 3268 Email: john.kelly@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionPUBLISHED
dcterms.projectinfo:eu-repo/grantAgreement/SFI/SFI Strategic Partnership Programme/14/SPP/B3051/IE/The opioid system as the brain's interface between cognition and motivation/en_IE
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland