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dc.contributor.authorKrukiewicz, Katarzyna
dc.contributor.authorFernandez, Jorge
dc.contributor.authorSkorupa, Małgorzata
dc.contributor.authorWięcławska, Daria
dc.contributor.authorPoudel, Anup
dc.contributor.authorSarasua, Jose-Ramon
dc.contributor.authorQuinlan, Leo R.
dc.contributor.authorBiggs, Manus J. P.
dc.date.accessioned2019-07-16T08:27:55Z
dc.date.available2019-07-16T08:27:55Z
dc.date.issued2019-04-15
dc.identifier.citationKrukiewicz, Katarzyna, Fernandez, Jorge, Skorupa, Małgorzata, Więcławska, Daria, Poudel, Anup, Sarasua, Jose-Ramon, Quinlan, Leo R., Biggs, Manus J. P. (2019). Analysis of a poly(ε-decalactone)/silver nanowire composite as an electrically conducting neural interface biomaterial. BMC Biomedical Engineering, 1(1), 9. doi: 10.1186/s42490-019-0010-3en_IE
dc.identifier.issn2524-4426
dc.identifier.urihttp://hdl.handle.net/10379/15260
dc.description.abstractAdvancement in polymer technologies, facilitated predominantly through chemical engineering approaches or through the identification and utilization of novel renewable resources, has been a steady focus of biomaterials research for the past 50 years. Aliphatic polyesters have been exploited in numerous biomedical applications including the formulation of soft-tissue sutures, bone fixation devices, cardiovascular stents etc. Biomimetic soft polymer formulations are of interest in the design of biological interfaces and specifically, in the development of implantable neuroelectrode systems intended to interface with neural tissues. Critically, soft polymer formulations have been shown to address the challenges associated with the disregulation of mechanotransductive processes and micro-motion induced inflammation at the electrode/tissue interface. In this study, a polyester-based poly(ε-decalactone)/silver nanowire (EDL:Ag) composite was investigated as a novel electrically active biomaterial with neural applications.en_IE
dc.description.sponsorshipThis publication has emanated from research conducted with the financial support of Science Foundation Ireland (SFI) and is co-funded under the European Regional Development Fund under Grant Number 13/RC/2073. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 713690 and SFI Technology Innovation Development Programme, grant no. 15/TIDA/2992. This work has been supported by the National Science Centre in Poland in the framework of Sonata 2016/23/D/ST5/01306. The authors acknowledge the facilities and scientific and technical assistance of the Center for Microscopy & Imaging at the National University of Ireland Galway, a facility that is funded by NUIG and the Irish Government’s Programme for Research in Third Level Institutions, Cycles 4 and 5, National Development Plan 2007–2013. These funding bodies had no role in design of study, and collection, analysis and interpretation of data and in writing the manuscript.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherBMC (part of Springer Nature)en_IE
dc.relation.ispartofBMC Biomedical Engineeringen
dc.subjectPolyestersen_IE
dc.subjectPoly(ε-decalactone)en_IE
dc.subjectSilver nanowiresen_IE
dc.subjectNeural interfacesen_IE
dc.subjectNeural stimulationen_IE
dc.titleAnalysis of a poly(ε-decalactone)/silver nanowire composite as an electrically conducting neural interface biomaterialen_IE
dc.typeArticleen_IE
dc.date.updated2019-07-08T08:32:12Z
dc.identifier.doi10.1186/s42490-019-0010-3
dc.local.publishedsourcehttps://doi.org/10.1186/s42490-019-0010-3en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funderScience Foundation Irelanden_IE
dc.contributor.funderEuropean Regional Development Funden_IE
dc.contributor.funderHorizon 2020en_IE
dc.contributor.funderNational Science Centre, Polanden_IE
dc.internal.rssid16797273
dc.local.contactKatarzyna Krukiewicz. Email: katarzyna.krukiewicz@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionPUBLISHED
dcterms.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/13/RC/2073/IE/C�RAM - Centre for Research in Medical Devices/en_IE
dcterms.projectinfo:eu-repo/grantAgreement/EC/H2020::MSCA-COFUND-FP/713690/EU/Career Development and Mobility Fellowships in Medical Device Research and Development: A CÚRAM Industry-Academia Training Initiative./MedTrainen_IE
dcterms.projectinfo:eu-repo/grantAgreement/SFI/SFI Technology and Innovation Development Award (TIDA)/15/TIDA/2992/IE/Biomimetic electrically conducting polymer scaffolds as novel neuromodulatory neuroelectrodes for the treatment of chronic pain/en_IE
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