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Advancements and challenges in multidomain multicargo delivery vehicles

dc.contributor.authorPugliese, Eugenia
dc.contributor.authorCoentro, João Q.
dc.contributor.authorZeugolis, Dimitrios I.
dc.date.accessioned2019-03-21T13:15:36Z
dc.date.available2019-03-21T13:15:36Z
dc.date.issued2018-02-15
dc.identifier.citationPugliese, Eugenia, Coentro, João Q., & Zeugolis, Dimitrios I. (2018). Advancements and Challenges in Multidomain Multicargo Delivery Vehicles. Advanced Materials, 30(13), 1704324. doi: 10.1002/adma.201704324en_IE
dc.identifier.issn1521-4095
dc.identifier.urihttp://hdl.handle.net/10379/15037
dc.description.abstractReparative and regenerative processes are well‐orchestrated temporal and spatial events that are governed by multiple cells, molecules, signaling pathways, and interactions thereof. Yet again, currently available implantable devices fail largely to recapitulate nature's complexity and sophistication in this regard. Herein, success stories and challenges in the field of layer‐by‐layer, composite, self‐assembly, and core shell technologies are discussed for the development of multidomain/multicargo delivery vehicles.en_IE
dc.description.sponsorshipE.P. and J.Q.C. contributed equally to this work. This work was supported by the Health Research Board, Health Research Awards Programme (Grant No. HRA_POR/2011/84), Science Foundation Ireland, Career Development Award (Grant No. 15/CDA/3629), Science Foundation Ireland/European Regional Development Fund (Grant No. 13/RC/2073), and H2020, Marie Skłodowska‐Curie Actions, Innovative Training Networks 2015 Tendon Therapy Train project (Grant No. 676338). This work is also part of the Teagasc Walsh Fellowship (Grant No. 2014045) and the ReValueProtein Research Project (Grant No. 11/F/043) and supported by the Department of Agriculture, Food and the Marine (DAFM) under the National Development Plan2007–2013 funded by the Irish Government. The authors would like to acknowledge Ella Maru Studio for designing all the figures of this manuscript.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherWileyen_IE
dc.relation.ispartofAdvanced Materialsen
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectcoaxial electrospinningen_IE
dc.subjectelectrosprayingen_IE
dc.subjectdendrimersen_IE
dc.subjectpolymersomesen_IE
dc.subjectmicellesen_IE
dc.subjectliposomesen_IE
dc.subjectmulticompartment biomaterialsen_IE
dc.subjectmultidrugen_IE
dc.subjectgeneen_IE
dc.subjectcell deliveryen_IE
dc.titleAdvancements and challenges in multidomain multicargo delivery vehiclesen_IE
dc.typeArticleen_IE
dc.date.updated2019-03-19T12:08:51Z
dc.identifier.doi10.1002/adma.201704324
dc.local.publishedsourcehttps://doi.org/10.1002/adma.201704324en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funderHealth Research Boarden_IE
dc.contributor.funderScience Foundation Irelanden_IE
dc.contributor.funderEuropean Regional Development Funden_IE
dc.contributor.funderHorizon 2020en_IE
dc.contributor.funderTeagasc Walsh Fellowshipen_IE
dc.contributor.funderDepartment of Agriculture, Food and the Marineen_IE
dc.internal.rssid16044444
dc.local.contactJoão Coentro, Remodel, Cúram, Biomedical Sciences Building, Newcastle Road, Dangan, Nui Galway. - Email: j.quintascoentro1@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionACCEPTED
dcterms.projectinfo:eu-repo/grantAgreement/SFI/SFI Career Development Award/15/CDA/3629/IE/Tissue Engineered Nanoassemblies _ Advanced Biomimicry of Living Equivalents (Short Title: TENABLE)/en_IE
dcterms.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/13/RC/2073/IE/C�RAM - Centre for Research in Medical Devices/en_IE
dcterms.projectinfo:eu-repo/grantAgreement/EC/H2020::MSCA-ITN-ETN/676338/EU/Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair/Tendon Therapy Trainen_IE
dcterms.projectinfo:eu-repo/grantAgreement/SFI/NSF/SFI Graduate Research Opportunities Worldwide (GROW) Programme/13/RC/2073s1/IE/C�RAM GROW Supplement/en_IE
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