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dc.contributor.authorDunne, Eoghan
dc.contributor.authorO'Halloran, Martin
dc.contributor.authorCraven, Darren
dc.contributor.authorPuri, Prem
dc.contributor.authorFrehill, Paul
dc.contributor.authorLoughney, Sarah
dc.contributor.authorPorter, Emily
dc.date.accessioned2019-03-15T14:30:13Z
dc.date.available2019-03-15T14:30:13Z
dc.date.issued2018-12-14
dc.identifier.citationDunne, E., Halloran, M. O', Craven, D., Puri, P., Frehill, P., Loughney, S., & Porter, E. (2018). Detection of Vesicoureteral Reflux using Electrical Impedance Tomography. IEEE Transactions on Biomedical Engineering, 1-1. doi: 10.1109/TBME.2018.2886830en_IE
dc.identifier.issn0018-9294
dc.identifier.urihttp://hdl.handle.net/10379/15030
dc.description.abstractObjective: The purpose of this study is to detect vesicoureteral reflux (VUR) non-invasively using electrical impedance tomography (EIT). VUR is characterized by the backflow of urine from the bladder to the kidneys. Methods: Using porcine models, small quantities of a solution mimicking the electrical properties of urine were infused into each ureter. EIT measurements were taken before, during and after the infusion using electrodes positioned around the abdomen. The collected data from 116 experiments were then processed and time-difference images reconstructed. Objective VUR detection was determined through statistical analysis of the mean change in the voltage signals and EIT image pixel intensities. Results: Unilateral VUR was successfully detected in 94.83% of all mean voltage signals and in over 98.28% of the reconstructed images. The images showed strong visual contrast between the region of interest and the background. Conclusion: In animal models, EIT has the capability to detect reflux in the kidneys with high accuracy. The results show promise for EIT to be used for screening of VUR in children. Significance: VUR is the most common congenital urinary tract abnormality in children. The condition predisposes children to urinary tract infections (UTIs) and kidney damage. The current gold standard diagnostic test, a voiding cystourethrogram (VCUG), is invasive and uses ionizing radiation; therefore, there is a need for new tools for identifying VUR in children. This study presents a non-invasive method to detect VUR in animal models, illustrating the potential for EIT as a screening tool in clinical scenarios.en_IE
dc.description.sponsorshipH2020 Health; FP7 People: Marie-Curie Actions; Ireland s European Structural and Investment Funds Programme 2014-2020;en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherIEEEen_IE
dc.relation.ispartofIeee Transactions On Biomedical Engineeringen
dc.subjectElectrical Impedance Tomographyen_IE
dc.subjectVesicoureteral Reflux (VUR)en_IE
dc.subjectAnimal Studyen_IE
dc.subjectKidneyen_IE
dc.subjectTomographyen_IE
dc.subjectElectrodesen_IE
dc.subjectAnimalsen_IE
dc.subjectBeltsen_IE
dc.subjectPediatricsen_IE
dc.subjectFabricsen_IE
dc.titleDetection of vesicoureteral reflux using electrical impedance tomographyen_IE
dc.typeArticleen_IE
dc.date.updated2019-02-26T13:15:40Z
dc.identifier.doi10.1109/TBME.2018.2886830
dc.local.publishedsourcehttps://dx.doi.org/10.1109/TBME.2018.2886830en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funderHorizon 2020en_IE
dc.contributor.funderSeventh Framework Programmeen_IE
dc.contributor.funderH2020 Marie Skłodowska-Curie Actionsen_IE
dc.internal.rssid15552875
dc.local.contactEoghan Dunne, -. - Email: e.dunne13@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionACCEPTED
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