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dc.contributor.advisorO'Halloran, Martin
dc.contributor.authorO'Loughlin, Declan Denis
dc.description.abstractRadar-based imaging is an emerging modality for breast cancer screening. Two commercial radar-based imaging devices are being tested in patient imaging studies. Promising initial results have highlighted the potential of the technology but have also identified that breast composition varies substantially from individual to individual. The breast composition is known to impact image quality, motivating the primary research objective: to develop novel radar-based breast imaging algorithms to address the normal variance of breast composition observed in the population. Firstly, fundamental assumptions of radar-based imaging algorithms are examined. The results of this analysis indicate that accounting for the dielectric properties of the patient-specific breast positively impacts the sensitivity of radar-based imaging in patient populations with normal breast variance. Using breast phantoms mimicking normal variation in breast composition, it is shown that using one population mean estimate of the dielectric properties may not be suitable to reconstruct images of all breasts. Secondly, a novel radar-based imaging algorithm is developed that can account for the dielectric properties of the patient-specific breast. The proposed algorithm is tested using experimental data from breast phantoms and also evaluated using five clinical case studies from the University of Calgary. The algorithm is applied to patients both with and without breast disease. These results suggest that the proposed algorithm can help improve the sensitivity in patients with breasts of differing tissue composition without impairing the specificity. However, both the experimental imaging results and clinical case studies highlight that achieving high specificity in dense breasts may be a potential challenge. More work needs to be done to investigate factors affecting the specificity of radar-based imaging. In summary, this thesis indicates that accounting for the patient-specific breast is important to achieve high sensitivity using radar-based breast imaging. A novel algorithm is proposed and tested that could be used to improve the sensitivity of radar-based breast imaging without negatively impacting the specificity.en_IE
dc.publisherNUI Galway
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.subjectRadar-based breast imagingen_IE
dc.subjectSensitivity Estimationen_IE
dc.subjectDielectric Properties Estimationen_IE
dc.subjectElectrical and Electronic Engineeringen_IE
dc.subjectCollege of Engineering and Informaticsen_IE
dc.subjectEngineering and Informaticsen_IE
dc.subjectElectrical and Electronic Engineeringen_IE
dc.titleImproving the sensitivity of radar-based breast imaging algorithms in diverse patient populationsen_IE
dc.contributor.funderIrish Research Councilen_IE
dc.local.noteRadar-based imaging is a promising emerging technique for breast cancer screening which is potentially safer, more comfortable and cheaper than x-ray mammography screening. This thesis describes a novel algorithm to increase the detection of early-stage breast cancers using radar-based imaging for women of all ages and breast types.en_IE

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Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland