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dc.contributor.authorZafar, Haroon
dc.contributor.authorLeahy, Martin
dc.contributor.authorWijns, William
dc.contributor.authorKolios, Michael C
dc.contributor.authorZafar, Junaid
dc.contributor.authorJohnson, Neil
dc.contributor.authorSharif, Faisal
dc.identifier.citationZafar, Haroon; Leahy, Martin; Wijns, William; Kolios, Michael C; Zafar, Junaid; Johnson, Neil; Sharif, Faisal (2018). Photoacoustic cardiovascular imaging: a new technique for imaging of atherosclerosis and vulnerable plaque detection. Biomedical Physics & Engineering Express 4 (3),
dc.description.abstractThe sudden rupture of an atherosclerotic plaque is one of the main causes of stroke and stroke induced death. Plaque composition plays a critical role in plaque rupture. In order to differentiate between different plaque components, an imaging technique suitable for patient follow-up is needed. Photoacoustic (PA) imaging (PAI), a relatively new imaging technique, can also be used for cardiovascular imaging as it resolves optical contrast with ultrasonic resolution, visualizes oxygenated and deoxygenated haemoglobin and a large range of optical agents. PAI can be used to visualize molecular tissue changes, not only stenosis, and relates to the evaluation treatment protocols and/or post-procedural follow-up. In this review, we explain the principles of PAI, describe the recent developments in PAI systems used for non-invasive carotid imaging and intravascular imaging of coronary atherosclerosis and suggest areas of future research that will help bring PAI imaging towards clinical cardiovascular imaging.
dc.publisherIOP Publishing
dc.relation.ispartofBiomedical Physics & Engineering Express
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.subjectcarotid imaging
dc.subjectduplex ultrasound
dc.subjectvulnerable plaque
dc.subjectcardiovascular imaging
dc.subjectintravascular imaging
dc.subjectoptical contrast agent
dc.subjectoptoacoustic tomography
dc.subjectgold nanoparticles
dc.subjectbiological tissues
dc.subjectcarotid plaque
dc.subjectthermoacoustic tomography
dc.subjectinterferometric detection
dc.titlePhotoacoustic cardiovascular imaging: a new technique for imaging of atherosclerosis and vulnerable plaque detection

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland