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dc.contributor.authorZafar, Haroon
dc.contributor.authorLeahy, Martin
dc.contributor.authorWijns, William
dc.contributor.authorKolios, Michael C
dc.contributor.authorZafar, Junaid
dc.contributor.authorJohnson, Neil
dc.contributor.authorSharif, Faisal
dc.date.accessioned2018-09-20T16:28:54Z
dc.date.available2018-09-20T16:28:54Z
dc.date.issued2018-03-13
dc.identifier.citationZafar, Haroon; Leahy, Martin; Wijns, William; Kolios, Michael C; Zafar, Junaid; Johnson, Neil; Sharif, Faisal (2018). Photoacoustic cardiovascular imaging: a new technique for imaging of atherosclerosis and vulnerable plaque detection. Biomedical Physics & Engineering Express 4 (3),
dc.identifier.issn2057-1976
dc.identifier.urihttp://hdl.handle.net/10379/14503
dc.description.abstractThe sudden rupture of an atherosclerotic plaque is one of the main causes of stroke and stroke induced death. Plaque composition plays a critical role in plaque rupture. In order to differentiate between different plaque components, an imaging technique suitable for patient follow-up is needed. Photoacoustic (PA) imaging (PAI), a relatively new imaging technique, can also be used for cardiovascular imaging as it resolves optical contrast with ultrasonic resolution, visualizes oxygenated and deoxygenated haemoglobin and a large range of optical agents. PAI can be used to visualize molecular tissue changes, not only stenosis, and relates to the evaluation treatment protocols and/or post-procedural follow-up. In this review, we explain the principles of PAI, describe the recent developments in PAI systems used for non-invasive carotid imaging and intravascular imaging of coronary atherosclerosis and suggest areas of future research that will help bring PAI imaging towards clinical cardiovascular imaging.
dc.publisherIOP Publishing
dc.relation.ispartofBiomedical Physics & Engineering Express
dc.subjectcarotid imaging
dc.subjectphotoacoustic
dc.subjectduplex ultrasound
dc.subjectvulnerable plaque
dc.subjectcardiovascular imaging
dc.subjectatherosclerosis
dc.subjectintravascular imaging
dc.subjectoptical contrast agent
dc.subjectin-vivo
dc.subjecthigh-resolution
dc.subjectoptoacoustic tomography
dc.subjectcomputed-tomography
dc.subjectgold nanoparticles
dc.subjectbiological tissues
dc.subjectcarotid plaque
dc.subjectthermoacoustic tomography
dc.subjectinterferometric detection
dc.titlePhotoacoustic cardiovascular imaging: a new technique for imaging of atherosclerosis and vulnerable plaque detection
dc.typeArticle
dc.identifier.doi10.1088/2057-1976/aab640
dc.local.publishedsourcehttp://iopscience.iop.org/article/10.1088/2057-1976/aab640/ampdf
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