Three-dimensional echocardiography vs. computed tomography for transcatheter aortic valve replacement sizing
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2015-10-01Author
Vaquerizo, Beatriz
Spaziano, Marco
Alali, Juwairia
Mylote, Darren
Theriault-Lauzier, Pascal
Alfagih, Rashed
Martucci, Giuseppe
Buithieu, Jean
Piazza, Nicolo
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Vaquerizo, Beatriz; Spaziano, Marco; Alali, Juwairia; Mylote, Darren; Theriault-Lauzier, Pascal; Alfagih, Rashed; Martucci, Giuseppe; Buithieu, Jean; Piazza, Nicolo (2015). Three-dimensional echocardiography vs. computed tomography for transcatheter aortic valve replacement sizing. European Heart Journal – Cardiovascular Imaging 17 (1), 15-23
Abstract
Aims The accuracy of transcatheter aortic valve replacement (TAVR) sizing using three-dimensional transoesophageal echocardiography (3D-TEE) compared with the gold-standard multi-slice computed tomography (MSCT) remains unclear. We compare aortic annulus measurements assessed using these two imaging modalities.
Methods and results We performed a single-centre prospective cohort study, including 53 consecutive patients undergoing TAVR, who had both MSCT and 3D-TEE for aortic annulus sizing. Aortic annular dimensions, expected transcatheter heart valve (THV) oversizing, and hypothetical valve size selection based on CT and TEE were compared. 3D-TEE and CT cross-sectional mean diameter (r = 0.69), perimeter (r = 0.70), and area (r = 0.67) were moderately to highly correlated (all P-values <0.0001). 3D-TEE-derived measurements were significantly smaller compared with MSCT: perimeter (68.6 +/- 5.9 vs. 75.1 +/- 5.7 mm, respectively; P < 0.0001); area (345.6 +/- 64.5 vs. 426.9 +/- 68.9 mm(2), respectively; P < 0.0001). The percentage difference between 3D-TEE and MSCT measurements was around 9%. Agreement between MSCT- and 3D-TEE-based THV sizing (perimeter) occurred in 44% of patients. Using the 3D-TEE perimeter annular measurements, up to 50% of patients would have received an inappropriate valve size according to manufacturer-recommended, area-derived sizing algorithms.
Conclusion Aortic annulus measurements for pre-procedural TAVR assessment by 3D-TEE are significantly smaller than MSCT. In this study, such discrepancy would have resulted in up to 50% of all patients receiving the wrong THV size. 3D-TEE should be used for TAVR sizing, only when MSCT is not available or contraindicated. The clinical impact of this information requires further study.