Browsing NUI Galway Theses (PhD Theses) by Author "Aldabbagh, Fawaz"
Now showing items 1-7 of 7
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Barton esters for initiator-free radical cyclisation with heteroaromatic substitution and anti-cancer evaluation of benzo[e][1,2,4]triazin-7-ones
Coyle, Robert (2014-07-03)Chapter 1 provides a general introduction to Chapters 2-5. Homolytic aromatic substitution routes to alicyclic ring-fused azoles and diazoles is reviewed. A review of recent literature using the COMPARE program of the ... -
The benign synthesis of bioactive heterocycles using photochemistry and hydrogen peroxide with hydrohalic acids
Gurry, Michael (2016-07-08)Chapter 1 provides a pertinent review of recent photochemical homolytic aromatic substitution (HAS) literature. Photochemical methods for HAS include UV-light and visible light photoredox catalysis. Recently invented methods ... -
Chain transfer to solvent in the radical polymerization of acrylamide monomers, controlled/living radical polymerizations, including in supercritical carbon dioxide and preparation of carbon dioxide responsive micelles
Magee, Christopher (2014-12-11)Chapter 1 provides a general introduction to radical polymerization, including chain transfer, and controlled/living radical polymerization. A review of the literature since 2009 on heterogeneous controlled/living radical ... -
First Synthesis of an Aziridinyl Fused Pyrrolo[1,2-a]benzimidazole and Cytotoxicity Evaluation of Various Imidazobenzimidazolequinones Towards Human Normal and Cancer Cell Lines
Bonham, Sarah (2011-07-13)Chapter 1 provides a review of aziridine containing anti-tumour agents and some key syntheses of the aziridinomitosene skeleton. A novel protocol for aziridine ring fusion is described leading to the preparation of the ... -
Synthesis and Anti-Cancer Activity of Novel Imidazo[5,4-f]benzimidazolequinones
Fagan, Vincent (2011-08-24)Chapter 1; A literature review of chemotherapeutic agents, bioreductive prodrugs and polycyclic diazoles, along with the aims and objects of the thesis is presented. Chapter 2; A review of 'oxidative' homolytic aromatic ... -
The use of Acetic Anhydride in Annulations onto Benzimidazoles to give Novel Reducible p-Dione Adducts
Joyce, Eamonn (2012-06-13)Chapter 1: Introduction to the reactive intermediates used in this thesis, namely acyl radicals and N-heterocyclic carbenes (NHC) is presented, along with an assessment of the anti-cancer activity of literature bioreductive ... -
The use of reversible addition-fragmentation chain transfer (RAFT) polymerization, supercritical carbon dioxide and new hetero-containing monomers in polymer chemistry
Hawkins, Gerard (2017-08-28)Chapter 1 is a general introduction with a description of conventional radical polymerization and reversible deactivation radical polymerizations for controlled/living techniques. In particular, the use of Reversible ...